Last reviewed 2026-04-20 · How we verify

Stromectol (ivermectin)

At a glance

Approved indications

• Infection by Onchocerca volvulus
• Infection by Strongyloides

Common side effects

• Pruritus
• Fever
• Skin involvement (edema, papular, pustular, urticarial rash)
• Inguinal lymph node enlargement
• Inguinal lymph node tenderness
• Axillary lymph node enlargement
• Arthralgia/synovitis
• Tachycardia
• Peripheral edema
• Dizziness
• Pruritus (strongyloidiasis)
• Cervical lymph node enlargement

Serious adverse events

• Anterior uveitis
• Chorioretinitis/choroiditis
• Keratitis
• Leukopenia
• Anemia
• Elevation in ALT/AST
• Decrease in leukocyte count

Key clinical trials

• Ivermectin and Doxycycline in Combination or Ivermectin Alone for the Treatment of Adult Bangladeshi Patients Hospitalized for COVID-19: a Randomised, Double-blind, Placebo-controlled Trial. (Phase 2)
• Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study) (Phase 2)
• A Double-Blind Randomized Study to Compare the Safety, Local Tolerability and Efficacy of a 0.5% Ivermectin Cream Compared to a Topical Vehicle Control in Subjects With Pediculus Humanus Capitis Infes (Phase 2)
• Repositioning Ivermectin for the Treatment of Alcohol Use Disorders (Phase 1)
• Analysis of the Microbiome in Rosacea (EARLY/Phase 1)
• A Single-Dose, Ivermectin-Controlled, Double-Blind, Efficacy, Safety And Tolerability Study Of Orally Administered Moxidectin In Subjects Infected With Onchocerca Volvulus (Phase 3)
• A Randomized Open-label Prophylaxis Trial Among Migrant Workers at High-risk of COVID-19 (DORM Trial) (Phase 3)
• Efficacy and Safety of Combination Moxidectin and Albendazole, Ivermectin and Albendazole and Albendazole Alone in Adolescents and Adults Infected With Trichuris Trichiura: a Randomized Controlled Tri (Phase 3)

Patents

Primary sources

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