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NCT04939922: CHRS

China Headache and Vertigo Registry Study

Recruiting now Last updated 25 July 2025
What this trial tests

trial in Headache Disorders, Primary in 10,000 participants. Currently enrolling.

Timeline
12 June 2017
Primary endpoint
12 December 2050
12 December 2050

Quick facts

Lead sponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment10,000
Start date12 June 2017
Primary completion12 December 2050
Estimated completion12 December 2050
Sites1 location across China

Conditions studied

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Who can join

Adults 4 to 99, any sex, with Headache Disorders, Primary or Headache Disorders, Secondary. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular migraine) and chronic pain (fibromyalgia and other diseases) were collected. The biomarkers, imaging features, right-to-left shunt of the heart (lung), genetic characteristics, treatment, and outcome (in relation to other diseases) of headache-related diseases were studied, and long-term follow-up was planned.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Increased iron deposition in nucleus accumbens associated with disease progression and chronicity in migraine.
    Xu X, Zhou M, Wu X, Zhao F, et al · · 2023 · cited 17× · PMID 37024948 · DOI 10.1186/s12916-023-02855-1
  2. The headache registry of the German Migraine and Headache Society (DMKG): baseline data of the first 1,351 patients.
    Ruscheweyh R, Klonowski T, Goßrau G, Kraya T, et al · · 2022 · cited 14× · PMID 35773650 · DOI 10.1186/s10194-022-01447-3
  3. Photophobia and Visual Triggers in Vestibular Migraine.
    Zou X, He J, Zhou M, Zhao F, et al · · 2024 · cited 4× · PMID 38819614 · DOI 10.1007/s40120-024-00631-8
  4. Positive Relationship Between Paroxysmal Vertigo and Right-to-Left Shunt: A Large Observational Study.
    Liu K, Tian X, Hong W, Xiao Y, et al · · 2022 · cited 4× · PMID 35720061 · DOI 10.3389/fneur.2022.927853
  5. Effectiveness of rimegepant in vestibular migraine: a prospective self-controlled cohort study.
    Shao J, Fu J, Zhou M, Ren Z, et al · · 2025 · PMID 41430107 · DOI 10.1186/s10194-025-02243-5
  6. Effectiveness of Rimegepant in Vestibular Migraine: A Prospective Self-controlled Cohort Study
    Shao J, Fu J, Zhou M, Ren Z, et al · · 2025 · DOI 10.21203/rs.3.rs-8009385/v1
  7. The Relationship Between Paroxysmal Vertigoes and Right-To-Left Shunt: A Large Observational Study
    Liu K, Tian X, Hong W, Xiao Y, et al · · 2021 · DOI 10.21203/rs.3.rs-1087535/v1

Verify or expand the search:

Other recruiting trials for Headache Disorders, Primary

Currently open trials in the same condition.

Other Second Affiliated Hospital, School of Medicine, Zhejiang University trials

Trials by the same sponsor.

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Data sources for this page

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