NCT04938778 is a NA clinical trial of PNF in Age-related Cognitive Decline, sponsored by Arizona State University.

Who is sponsoring NCT04938778?

NCT04938778 is sponsored by Arizona State University.

What drugs are being tested in NCT04938778?

Interventions in NCT04938778: PNF.

What condition does NCT04938778 study?

NCT04938778 studies Age-related Cognitive Decline.

Is NCT04938778 still recruiting?

NCT04938778 is currently completed. Last updated 4 August 2022.

Last reviewed 2022-08-04 · How we verify

NCT04938778

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Think FAST Research Study

Completed NA Last updated 4 August 2022

What this trial tests

NA trial testing PNF in Age-related Cognitive Decline in 20 participants. Completed in 30 July 2022.

Timeline

1 February 2021

Primary endpoint
30 July 2022

30 July 2022

Quick facts

Lead sponsor	Arizona State University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	20
Start date	1 February 2021
Primary completion	30 July 2022
Estimated completion	30 July 2022
Sites	1 location across United States

Drugs / interventions tested

Conditions studied

Age-related Cognitive Decline — all drugs for Age-related Cognitive Decline →

Sponsor

Arizona State University

Who can join

65 and older, any sex, with Age-related Cognitive Decline. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To test a 14-hour prolonged nightly fasting (PNF) protocol in a group of older adults (≥ 65 years old) with self-identified age-related cognitive decline (ARCD) on the primary outcome of neurocognitive function and performance as measured by objective outcomes. The investigators will use an 8-week single group pre-post pilot study design to measure outcomes related to neurocognitive function and performance and cardiometabolic risk factors (i.e., sleep disturbances, body mass index).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors.
James DL, Larkey LK, Maxfield M, Han S, et al · · 2025 · cited 7× · PMID 39830610 · DOI 10.1017/cts.2024.676
Perspectives of older adults with memory decline participating in a prolonged nightly fasting (PNF) pilot study: A qualitative exploration.
James DL, Ahlich E, Maxfield M, Kechter A, et al · · 2025 · PMID 40529001 · DOI 10.1017/cts.2025.63

Verify or expand the search:

Other trials of PNF

Trials testing the same drug.

NCT07381491 — Effects of Core Strengthening With Pelvic Proprioceptive Neuromuscular Facilitation on Trunk Control and Balance in Pati · NA · recruiting
NCT07331714 — Comparative Effects of PNF and mCIMT on Lower Limb Function in Patient With Stroke · NA · completed
NCT06803459 — Effects of Baduanjin and PNF on Upper Crossed Syndrome Among University Students in Henan Province，China · NA · completed
NCT07205770 — Comparison of Stretching Methods in Individuals With Scoliosis · NA · completed
NCT05876403 — Respiratory Proprioceptive Neuromuscular Facilitation Technique in Chronic Pulmonary Obstructive Disease Patients. · NA · completed

Other recruiting trials for Age-related Cognitive Decline

Currently open trials in the same condition.

NCT06948136 — Acute Effects of THC in Older Adult · Phase 1 · recruiting
NCT06964399 — The Effect of Reminiscence Therapy in Elderly · NA · recruiting
NCT06893432 — Cognitive Function and EEG Brain Network Remodeling Among Users of Hearing Aids With ARHL · active not recruiting
NCT06377254 — Multi-organ Responses to CHronic Physical Activity and INactivity · NA · recruiting
NCT04184375 — Cognitive Stimulation for Elderly Bipolar Patients · NA · recruiting

Other Arizona State University trials

Trials by the same sponsor.

NCT07519408 — Acute Kidney Injury and Ultra-endurance Running · NA · not yet recruiting
NCT05784467 — Methamphetamine, PrEP, and Intersectional Stigma Study · NA · not yet recruiting
NCT07375043 — Drumming Groups for Parents of Autistic Children · NA · not yet recruiting
NCT07297901 — App-based Breathing Program for Migraine Relief · NA · enrolling by invitation
NCT06721793 — The Impact of a Caffeinated Sports Drink on Performance · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04938778 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Arizona State University
Last refreshed: 4 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04938778.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing