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NCT04934644: ORN
The Effect of Hyperbaric Oxygen Treatment in Patients With Osteoradionecrosis.
NA trial testing Hyperbaric oxygen treatment in Osteoradionecrosis in 120 participants. Status unknown.
19 March 2024
Quick facts
| Lead sponsor | Göteborg University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 19 March 2019 |
| Primary completion | 19 March 2024 |
| Estimated completion | 19 March 2024 |
| Sites | 2 locations across Sweden |
Drugs / interventions tested
- Hyperbaric oxygen treatment — full drug profile →
Conditions studied
- Osteoradionecrosis — all drugs for Osteoradionecrosis →
Sponsor
Göteborg University
Who can join
18 and older, any sex, with Osteoradionecrosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Osteoradionecrosis (ORN) is a severe delayed radiation-induced injury that can occur in patients whom have been subjected to radiotherapy for head and neck cancer. Hyperbaric oxygen treatment (HBO) is one treatment option. In Sweden it is used in some locations in combination to standard treatment which includes for example antibiotics, pain medication and surgery. There is still not sufficient evidence that this treatment is effective in this group of patients. The primary aim of this study will be to evaluate HBO as a treatment for osteoradionecrosis in terms of slowing the progression of the disease, or at the best, cure the disease.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04934644
- Europe PMC full search
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Related trials
Other trials of Hyperbaric oxygen treatment
Trials testing the same drug.
- NCT07489274 — Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial). · Phase 4 · not yet recruiting
- NCT07410169 — Efficacy and Safety of Hyperbaric Oxygen Therapy in Improving Nab-paclitaxel-Induced Peripheral Neuropathy · Phase 2, PHASE3 · not yet recruiting
- NCT06819202 — Effect of Hyperbaric Oxygen Therapy(HBOT) on Patients With Sudden Sensorineural Hearing Loss(SSNHL) and Coagulation Func · not yet recruiting
- NCT06825949 — A Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Hormone Recepto · NA · not yet recruiting
- NCT06825975 — A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatmen · NA · not yet recruiting
Other recruiting trials for Osteoradionecrosis
Currently open trials in the same condition.
- NCT04265430 — Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral · Phase 4 · recruiting
Other Göteborg University trials
Trials by the same sponsor.
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- NCT07178405 — Effects of Meal Characteristics on Appetite · NA · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04934644 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Göteborg University
- Last refreshed: 22 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04934644.
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