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NCT04921280
Effectiveness of ICBT for Severe Health Anxiety in Clinical Psychiatry.
trial testing Internet based Cognitive Behavioural Therapy in Health Anxiety in 456 participants. Completed in 15 March 2021.
15 March 2021
Quick facts
| Lead sponsor | Karolinska Institutet |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 456 |
| Start date | 1 April 2018 |
| Primary completion | 15 March 2021 |
| Estimated completion | 15 March 2021 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Internet based Cognitive Behavioural Therapy
Conditions studied
- Health Anxiety — all drugs for Health Anxiety →
- Hypochondriasis — all drugs for Hypochondriasis →
- Illness Anxiety Disorder — all drugs for Illness Anxiety Disorder →
- Somatic Symptom Disorder — all drugs for Somatic Symptom Disorder →
Sponsor
Karolinska Institutet
Who can join
16 and older, any sex, with Health Anxiety or Hypochondriasis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate the clinical effectiveness of internet-based cognitive therapy for severe health anxiety within regular psychiatric care. A longitudinal cohort study will be conducted investigating 400 patients who have received ICBT for severe health anxiety between 2018-2020 in an outpatient psychiatric clinic providing Internet-based treatment. The primary outcome measure will be the Short Health Anxiety Inventory, SHAI, and a within-group design with repeated measures will be used for primary analysis. It is hypothesized that ICBT will be associated with a significant reduction in health anxiety as measured with SHAI, both after treatment and at six-month follow-up.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effectiveness and prediction of treatment adherence to guided internet-based cognitive behavioral therapy for health anxiety: A cohort study in routine psychiatric care.
Österman S, Axelsson E, Forsell E, Svanborg C, et al · · 2024 · cited 4× · PMID 39498477 · DOI 10.1016/j.invent.2024.100780
Verify or expand the search:
- PubMed search for NCT04921280
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04921280 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
- Last refreshed: 29 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04921280.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing