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NCT04921046
Effect of Pretreatment of Lignocaine Versus Midazolam in Prevention of Etomidate Induced Myoclonus.
Phase 4 trial testing lignocaine in Myoclonic Jerk in 224 participants. Completed in 30 June 2015.
30 June 2015
Quick facts
| Lead sponsor | Rawalpindi Medical College |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 224 |
| Start date | 1 January 2015 |
| Primary completion | 30 June 2015 |
| Estimated completion | 30 June 2015 |
Drugs / interventions tested
- lignocaine — full drug profile →
- Midazolam 1 milligram Prefilled Syringe — full drug profile →
Conditions studied
- Myoclonic Jerk — all drugs for Myoclonic Jerk →
Sponsor
Rawalpindi Medical College
Who can join
Adults 20 to 45, any sex, with Myoclonic Jerk. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a randomized control trial and it was conducted to compare the effectiveness of pretreatment with lignocaine versus midazolam on the frequency of myoclonus associated with etomidate induction. This was conducted in Holy Family Hospital Rawalpindi in a period of 6 months.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04921046
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04921046 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rawalpindi Medical College
- Last refreshed: 10 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04921046.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing