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NCT04914975: FES_Bowel
The Effect of NMES on Bowel Management in People With Chronic SCI
NA trial testing Neuromuscular electrical stimulation in Electric Stimulation Therapy in 20 participants. Completed in 30 October 2024.
31 August 2024
Quick facts
| Lead sponsor | Swiss Paraplegic Research, Nottwil |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 4 July 2021 |
| Primary completion | 31 August 2024 |
| Estimated completion | 30 October 2024 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Neuromuscular electrical stimulation
Conditions studied
- Electric Stimulation Therapy — all drugs for Electric Stimulation Therapy →
- Bowel Dysfunction — all drugs for Bowel Dysfunction →
- Spinal Cord Injuries — all drugs for Spinal Cord Injuries →
- Defecation Disorder — all drugs for Defecation Disorder →
Sponsor
Swiss Paraplegic Research, Nottwil — full company profile →
Who can join
18 and older, any sex, with Electric Stimulation Therapy or Bowel Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It has been reported that 62% of all people with Spinal Cord Injury (SCI) have experienced faecal incontinence and that neurogenic bowel dysfunction (NBD) is a major sequela. As an alternative to abdominal massage or the use of suppositories, the electrical stimulation (ES) of the abdominal wall has been shown to be effective in decreasing the bowel transit time as well as decreasing constipation in children with slow-transit constipation. Due to the intrinsic nature of the guts' innervation, we expect to reproduce these positive effects in people with SCI through administration of neuromuscular electrical stimulation (NMES).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The effect of neuromuscular electrical stimulation on bowel management in people with chronic spinal cord injury-An IDEAL 2a pilot study.
Bersch I, Schafer K, Limacher A, Sonntag U, et al · · 2025 · PMID 41146588 · DOI 10.1111/codi.70276
Verify or expand the search:
- PubMed search for NCT04914975
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Neuromuscular electrical stimulation
Trials testing the same drug.
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- NCT07531381 — Effect of Neuromuscular Electrical Stimulation With Task Oriented Training on Upper Extremity Function in Stroke Patient · NA · completed
- NCT07367490 — Neuromuscular Electrical Stimulation Versus Electromyographic Biofeedback on Oropharyngeal Dysphagia in Patients With St · NA · completed
- NCT06516770 — Movement Control and Motor Unit Behavior Responses to Different Types of Stimulation · NA · active not recruiting
- NCT06316349 — Isolated Resistance Training and Neuromuscular Electrical Stimulation in Patients With Femoral Intra Aortic Balloon Pump · NA · recruiting
Other recruiting trials for Electric Stimulation Therapy
Currently open trials in the same condition.
- NCT06520020 — Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal · NA · recruiting
- NCT00739362 — Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment · Phase 2 · recruiting
Other Swiss Paraplegic Research, Nottwil trials
Trials by the same sponsor.
- NCT07456722 — Cardiac Morphology and Function in Individuals With Autonomic Dysreflexia · not yet recruiting
- NCT06905470 — The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation · NA · not yet recruiting
- NCT07165353 — Virtual Walking to Reduce Chronic Neuropathic Pain in Subjects With SCI · NA · recruiting
- NCT06892080 — Urine Incontinence Occurrence and Sexual Hormones in Women With Chronic Spinal Cord Injury/Disease - a Pilot Study · recruiting
- NCT06633588 — Decolonization Efficacy of Polyhexanide vs. Mupirocin · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04914975 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Swiss Paraplegic Research, Nottwil
- Last refreshed: 9 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04914975.
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