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NCT04909476
Tracheal Intubation in COVID-19 Patients
trial testing Endotracheal intubation in COVID-19 Pneumonia in 143 participants. Status unknown.
20 May 2021
Quick facts
| Lead sponsor | St. Bortolo Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 143 |
| Start date | 17 November 2020 |
| Primary completion | 20 May 2021 |
| Estimated completion | 10 June 2021 |
| Sites | 2 locations across Italy |
Drugs / interventions tested
- Endotracheal intubation
Conditions studied
- COVID-19 Pneumonia — all drugs for COVID-19 Pneumonia →
- Tracheal Intubation — all drugs for Tracheal Intubation →
Sponsor
St. Bortolo Hospital
Who can join
18 and older, any sex, with COVID-19 Pneumonia or Tracheal Intubation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Emergency Endotracheal intubation of a patient who is COVID-19 positive is a high-risk procedure and an additional challenge to an intensivist due to barrier enclosures that have been developed to reduce the risk of COVID-19 transmission to healthcare providers during intubation. Although the incidence of difficult airways is commonly higher in critically ill patients, the evidence of severe hypoxemia without sign of respiratory distress could complicate the scenario.This silent hypoxia often leads to a delayed recognition of the severity of respiratory failure and to a late intubation which is often characterized by a high risk of complications related to the actual airways' management, hemodynamic and cardiac. It has been shown that non-survivors had worse blood gas analyzes than survivors, both before and after intubation. Few studies have reported the implications and adverse events of performing endotracheal intubation for critically ill COVID-19 patients admitted to intensive care units (ICUs).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Airways management in SARS-COV-2 acute respiratory failure: A prospective observational multi-center study.
Cattin L, Ferrari F, Mongodi S, Pariani E, et al · · 2023 · cited 9× · PMID 36855737 · DOI 10.1016/j.medin.2022.07.002 -
Airways management in SARS-COV-2 acute respiratory failure: A prospective observational multi-center study.
Cattin L, Ferrari F, Mongodi S, Pariani E, et al · · 2023 · cited 1× · PMID 36155747 · DOI 10.1016/j.medine.2022.08.005
Verify or expand the search:
- PubMed search for NCT04909476
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT06558630 — ED Airway Management in the Netherlands. · recruiting
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Other recruiting trials for COVID-19 Pneumonia
Currently open trials in the same condition.
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- NCT05765396 — SARS-CoV-2/COVID-19 Study of Next Generation Non-Invasive Passive Detection Technologies · active not recruiting
- NCT06927622 — Corona Virus Disease 2019 Cohort Study · recruiting
Other St. Bortolo Hospital trials
Trials by the same sponsor.
- NCT04905875 — Prone Positioning for Invasively Ventilated Patients With COVID-19 Registry · unknown
- NCT03747731 — A Non-invasive Evaluation of Kidney-Lung Interactions · unknown
- NCT03489759 — The Effect of Vitamin E-coated Polysulfone Membrane on Oxidative Stress, Inflammation and Monocytes in Critically Ill Pa · NA · unknown
- NCT03443219 — RCT- LMA Supreme™ Versus the Spritztube® Tracheal Cannula in Anesthetized Adult Patients · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04909476 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Bortolo Hospital
- Last refreshed: 4 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04909476.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing