NCT04905875 (PROVENT-C19) is a clinical trial of Prone Position in COVID-19 Pneumonia, sponsored by St. Bortolo Hospital.

Who is sponsoring NCT04905875?

NCT04905875 is sponsored by St. Bortolo Hospital.

What drugs are being tested in NCT04905875?

Interventions in NCT04905875: Prone Position.

What condition does NCT04905875 study?

NCT04905875 studies COVID-19 Pneumonia.

Is NCT04905875 still recruiting?

NCT04905875 is currently status unknown. Last updated 1 June 2021.

Last reviewed 2021-06-01 · How we verify

NCT04905875: PROVENT-C19

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prone Positioning for Invasively Ventilated Patients With COVID-19 Registry

Status unknown Last updated 1 June 2021

What this trial tests

trial testing Prone Position in COVID-19 Pneumonia in 1,000 participants. Status unknown.

Timeline

1 December 2020

Primary endpoint
1 May 2022

1 May 2022

Quick facts

Lead sponsor	St. Bortolo Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	1 December 2020
Primary completion	1 May 2022
Estimated completion	1 May 2022
Sites	1 location across Italy

Drugs / interventions tested

Prone Position

Conditions studied

COVID-19 Pneumonia — all drugs for COVID-19 Pneumonia →

Sponsor

St. Bortolo Hospital

Who can join

18 and older, any sex, with COVID-19 Pneumonia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

SARS-CoV-2 infection is characterized mainly by moderate/severe pneumonia associated with progressive endothelial damage and coagulopathy. Acute respiratory failure among COVID-19 occurs in 42% of patients with COVID-19 pneumonia, and 61-81% of patients requiring intensive care . Among the suggested treatments for the management of ARDS patients, prone position (PP) can be used as an adjuvant therapy for improving ventilation in these patients, as recommended in the Surviving Sepsis Campaign COVID-19 guidelines. Nevertheless, no data is currently available on application and feasibility of PP in invasively ventilated patients with COVID-19 on their outcomes.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The PROVENT-C19 registry: A study protocol for international multicenter SIAARTI registry on the use of prone positioning in mechanically ventilated patients with COVID-19 ARDS.
De Rosa S, Sella N, Rezoagli E, Lorenzoni G, et al · · 2022 · cited 5× · PMID 36584022 · DOI 10.1371/journal.pone.0276261

Verify or expand the search:

Other trials of Prone Position

Trials testing the same drug.

NCT05434364 — Comparison Three Methods on Endotracheal Aspiration in Preterm Infants · NA · completed
NCT06025370 — Pressures During Prone Positions in Healthy Volunteers · NA · completed
NCT06997666 — Effect of Prone Position on Oxygen, Blood Gas, and Respiratory Parameters in Intensive Care Patients With COVID-19-induc · NA · completed
NCT04158271 — Evaluation of Techniques for Tracheal Tube Exchange in Standard and Critical Care Patients · NA · completed

Other recruiting trials for COVID-19 Pneumonia

Currently open trials in the same condition.

NCT06601998 — Cardiovascular Disease Progression in Survivors of Community Acquired Pneumonia and Lung Infection by Covid-19. · recruiting
NCT06501599 — AI-based System for Assessing Suspected Viral Pneumonia Related Lung Changes · recruiting
NCT06402318 — Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine · recruiting
NCT05765396 — SARS-CoV-2/COVID-19 Study of Next Generation Non-Invasive Passive Detection Technologies · active not recruiting
NCT06927622 — Corona Virus Disease 2019 Cohort Study · recruiting

Other St. Bortolo Hospital trials

Trials by the same sponsor.

NCT04909476 — Tracheal Intubation in COVID-19 Patients · unknown
NCT03747731 — A Non-invasive Evaluation of Kidney-Lung Interactions · unknown
NCT03489759 — The Effect of Vitamin E-coated Polysulfone Membrane on Oxidative Stress, Inflammation and Monocytes in Critically Ill Pa · NA · unknown
NCT03443219 — RCT- LMA Supreme™ Versus the Spritztube® Tracheal Cannula in Anesthetized Adult Patients · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04905875 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by St. Bortolo Hospital
Last refreshed: 1 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04905875.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing