Who is sponsoring NCT04891458?

NCT04891458 is sponsored by Hebei Medical University Third Hospital.

What drugs are being tested in NCT04891458?

Interventions in NCT04891458: Patients received lighter sedation with propofol after spinal anesthesia., Patients received heavier sedation with propofol after spinal anesthesia, Patients received lighter sedation with dexmedetomidine after spinal anesthesia, Patients received heavier sedation with dexmedetomidine after spinal anesthesia..

What condition does NCT04891458 study?

NCT04891458 studies Elderly, Anesthesia.

Is NCT04891458 still recruiting?

NCT04891458 is currently status unknown. Last updated 18 May 2021.

Last reviewed 2021-05-18 · How we verify

NCT04891458

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Intraoperative Sedation on PND in Elderly Patients

Status unknown NA Last updated 18 May 2021

What this trial tests

NA trial testing Patients received lighter sedation with propofol after spinal anesthesia. in Elderly in 160 participants. Status unknown.

Timeline

1 July 2021

Primary endpoint
30 June 2022

31 July 2022

Quick facts

Lead sponsor	Hebei Medical University Third Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	160
Start date	1 July 2021
Primary completion	30 June 2022
Estimated completion	31 July 2022

Drugs / interventions tested

Patients received lighter sedation with propofol after spinal anesthesia. — full drug profile →
Patients received heavier sedation with propofol after spinal anesthesia — full drug profile →
Patients received lighter sedation with dexmedetomidine after spinal anesthesia — full drug profile →
Patients received heavier sedation with dexmedetomidine after spinal anesthesia. — full drug profile →

Conditions studied

Elderly — all drugs for Elderly →
Anesthesia — all drugs for Anesthesia →

Sponsor

Hebei Medical University Third Hospital

Who can join

65 and older, any sex, with Elderly or Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study was to identify the effects of different depths of sedation and choices of sedative drugs on perioperative neurocognitive disorders in the elderly patients receiving hip surgery under spinal anesthesia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Different Sedation Strategies in Older Patients Receiving Spinal Anesthesia for Hip Surgery on Postoperative Delirium: A Randomized Clinical Trial.
Zhu S, Liu Y, Wang X, Wang L, et al · · 2023 · cited 9× · PMID 38169975 · DOI 10.2147/dddt.s439543

Verify or expand the search:

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Other Hebei Medical University Third Hospital trials

Trials by the same sponsor.

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NCT05030259 — The Research About the ACS After Femoropopliteal Arterial Injuries · recruiting
NCT05585216 — The Efficacy of PRP Combined With Exercise to Treat Knee Osteoarthritisq · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04891458 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hebei Medical University Third Hospital
Last refreshed: 18 May 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04891458.

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