NCT04891367

Cognitive Behavioral Group Treatment for Obsessive-compulsive Disorder in Youth

Status unknown NA Last updated 27 September 2022

What this trial tests

NA trial testing Cognitive behavioral therapy in Obsessive-Compulsive Disorder in 72 participants. Status unknown.

Timeline

15 August 2017

Primary endpoint
30 June 2025

30 June 2025

Quick facts

Lead sponsor	Aarhus University Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	72
Start date	15 August 2017
Primary completion	30 June 2025
Estimated completion	30 June 2025
Sites	1 location across Denmark

Drugs / interventions tested

• Cognitive behavioral therapy

Conditions studied

• Obsessive-Compulsive Disorder — all drugs for Obsessive-Compulsive Disorder →
• Cognitive Behavioral Therapy — all drugs for Cognitive Behavioral Therapy →
• Adolescent — all drugs for Adolescent →

Sponsor

Aarhus University Hospital

Who can join

Adults 13 to 17, any sex, with Obsessive-Compulsive Disorder or Cognitive Behavioral Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Obsessive-compulsive disorder (OCD) is a debilitating disorder characterized by unwanted intrusive thoughts and disrupting repetitive rituals. Epidemiological studies estimate the prevalence of impairing OCD to be between 0.5-3.0 % in pediatric populations. Although OCD in youth is associated with substantial distress and functional impairment, access to evidence-based psychosocial treatments is limited. This is largely due to the fact that few clinicians are trained in the delivery of evidence-based treatments, such as exposure-based cognitive-behavioral therapy (CBT). Therefore it is of great importance to develop treatment programs that utilize therapist resources in the most efficient way.

Exposure-based CBT delivered in the context of a group, rather than individually, is one such option. However, there are currently no evidence-based group OCD treatment manuals for youth available to clinicians in Denmark. Therefore this project addresses an important clinical need. We evaluate a group-based CBT protocol for the treatment of youth with OCD, benchmarking treatment outcomes against data from a previous trial evaluating individual-based CBT and by comparing outcomes against a short waiting list period. Further, we will explore the impact of group-based CBT over a 36-month open follow-up interval on general functioning, relapse, recurrence rates, and the need for other treatments. Finally, a brief youth questionnaire assessing overall symptom severity relevant for the evaluation of outcomes in pediatric OCD will be translated and validated for future clinical and research use in Denmark.

The project will include 72 adolescents with a primary diagnosis of OCD referred for assessment and treatment at the OCD Clinic at Department of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark. For benchmarking of treatment outcomes, the project will compare the results from the group-based CBT with data from 45 Danish patients previously enrolled in the individual-based CBT of the Nordic Long Term OCD Treatment Study at the same clinic.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Helpful and hindering factors in group-based cognitive-behavioral therapy for adolescents with obsessive-compulsive disorder: a qualitative study.
   Jensen S, Bryde A, Nielsen MS, Thomsen LH, et al · · 2026 · PMID 41882610 · DOI 10.1186/s12888-026-08007-y
2. Parental involvement in cognitive behavioral group treatment for adolescents with obsessive-compulsive disorder: a qualitative study.
   Nielsen MS, Thomsen LH, Hybel KA, Nissen J, et al · · 2026 · PMID 41872781 · DOI 10.1186/s12888-026-08003-2