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NCT04890483
tDCS in Post-Acute COVID-19 Patients With SARDs
NA trial testing Transcranial direct current stimulation in Rheumatic Diseases in 20 participants. Currently enrolling.
6 May 2024
Quick facts
| Lead sponsor | University of Sao Paulo |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 17 May 2021 |
| Primary completion | 6 May 2024 |
| Estimated completion | 4 December 2024 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Transcranial direct current stimulation
Conditions studied
- Rheumatic Diseases — all drugs for Rheumatic Diseases →
- Autoimmune Diseases — all drugs for Autoimmune Diseases →
Sponsor
University of Sao Paulo
Who can join
Adults 18 to 80, any sex, with Rheumatic Diseases or Autoimmune Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Some patients develop "Post-acute COVID-19 syndrome," in which they experience persistent symptoms after recovering from the acute phase of COVID-19 infection. This syndrome may be more significant in patients with systemic autoimmune rheumatic diseases (SARDs) who have been suffering from several symptoms associated to SARDs, such as myalgia, fatigue, and general pains. The transcranial direct current stimulation (tDCS) technique has been frequent, for example, to relieve fatigue and general pains in general population. However, to date, there are no studies evaluating this technique in ARD patients with post-acute COVID-19; therefore, the main objective of the opened study is to evaluate the safety and efficacy of the application of acute tDCS in ARD patients with post-acute COVID-19.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Transcranial direct current electrical stimulation in combination with aerobic exercise is effective in reducing fatigue and pain in post-COVID-19 systemic autoimmune rheumatic patients
Missé RG, Santos AMd, Borges IBP, Simões MSM, et al · · 2021 · DOI 10.21203/rs.3.rs-1008362/v1
Verify or expand the search:
- PubMed search for NCT04890483
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04890483 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
- Last refreshed: 5 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04890483.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing