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NCT04880538
Enteric Neural Precursor Cells (ENPC) in the Human Gut
trial testing Endoscopic procedure in Gastrointestinal Dysmotility in 5 participants. Completed in 11 September 2023.
11 September 2023
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 5 |
| Start date | 26 April 2021 |
| Primary completion | 11 September 2023 |
| Estimated completion | 11 September 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Endoscopic procedure
Conditions studied
- Gastrointestinal Dysmotility — all drugs for Gastrointestinal Dysmotility →
Sponsor
Johns Hopkins University
Who can join
Adults 18 to 100, any sex, with Gastrointestinal Dysmotility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aim is to acquire human tissues to (a) understand the structure and organization of the human Enteric Nervous System; (b) perform a molecular transcriptomic profile of individual cells residing in the human gut; (c) study the turnover rates of individual cell types by Fluorescence-activated cell sorting-aided C14 dating of cells; and finally (d) culture the human gut-derived cells characterize the human adult enteric neural stem cell and study its potential for Neuro-glial differentiation. This study will advance our knowledge of the the cellular and molecular correlates of changes in the Enteric Nervous System that are associated with disorders of motility.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04880538
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04880538 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 15 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04880538.
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