NCT04853446 (ADJUNCT1) is a Phase 4 clinical trial of Dexamethasone 12 mg in Anesthesia, Local, sponsored by Zealand University Hospital.

Who is sponsoring NCT04853446?

NCT04853446 is sponsored by Zealand University Hospital.

What drugs are being tested in NCT04853446?

Interventions in NCT04853446: Dexamethasone 12 mg, Placebo, Dexamethasone 24 mg.

What condition does NCT04853446 study?

NCT04853446 studies Anesthesia, Local.

Is NCT04853446 still recruiting?

NCT04853446 is currently completed. Last updated 25 May 2023.

Last reviewed 2023-05-25 · How we verify

NCT04853446: ADJUNCT1

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oral Dexamethasone as an Adjunct to a Brachial Plexus Block in Patients Undergoing Orthopaedic Surgery of the Forearm and Hand

Completed Phase 4 Last updated 25 May 2023

What this trial tests

Phase 4 trial testing Dexamethasone 12 mg in Anesthesia, Local in 180 participants. Completed in 4 May 2023.

Timeline

28 June 2021

Primary endpoint
4 April 2023

4 May 2023

Quick facts

Lead sponsor	Zealand University Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	180
Start date	28 June 2021
Primary completion	4 April 2023
Estimated completion	4 May 2023
Sites	3 locations across Denmark

Drugs / interventions tested

Dexamethasone 12 mg — full drug profile →
Placebo
Dexamethasone 24 mg — full drug profile →

Conditions studied

Anesthesia, Local — all drugs for Anesthesia, Local →

Sponsor

Zealand University Hospital

Who can join

18 and older, any sex, with Anesthesia, Local. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators will assess the beneficial and harmful effects of oral dexamethasone (12 mg or 24 mg) versus placebo in patients undergoing orthopaedic surgery of their hand or forearm with a lateral infraclavicular brachial plexus block as the means of providing anaesthesia and analgesia.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Dexamethasone 12 mg

Trials testing the same drug.

NCT04818749 — Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients U · Phase 4 · completed
NCT01975727 — Dexamethasone for the Treatment of Established Postoperative Nausea and Vomiting · Phase 2 · terminated

Other recruiting trials for Anesthesia, Local

Currently open trials in the same condition.

NCT07337772 — Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty · NA · recruiting
NCT06960317 — Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements · NA · recruiting
NCT06694714 — Split Face Study of the Duration of Local Anesthetics - Fourth Arm · Phase 4 · recruiting
NCT04706026 — A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults · NA · recruiting
NCT06528288 — Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery · NA · recruiting

Other Zealand University Hospital trials

Trials by the same sponsor.

NCT07373561 — Post-Intensive Care Syndrome and Associated Symptom Burden Among Danish ICU Survivors · not yet recruiting
NCT07386080 — Carbergoline for Antipsychotic Induced Hyperprolactinemia. · Phase 4 · not yet recruiting
NCT07482150 — The Connect Trial: Connecting Hospital Patients to Alcohol Care · NA · not yet recruiting
NCT07460999 — Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) · NA · recruiting
NCT07365527 — Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04853446 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Zealand University Hospital
Last refreshed: 25 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04853446.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing