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NCT04832633
The Best Parameters for Imaging Agent Injection and Scanning Methods in Computed Tomography Angiography
NA trial testing Different contrast media injection methods in Enhancement of Aorta and Pulmonary Artery in 101 participants. Completed in 28 February 2020.
28 February 2020
Quick facts
| Lead sponsor | Mackay Memorial Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 101 |
| Start date | 1 March 2018 |
| Primary completion | 28 February 2020 |
| Estimated completion | 28 February 2020 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Different contrast media injection methods
Conditions studied
- Enhancement of Aorta and Pulmonary Artery — all drugs for Enhancement of Aorta and Pulmonary Artery →
- Radiation Exposure — all drugs for Radiation Exposure →
Sponsor
Mackay Memorial Hospital
Who can join
20 and older, any sex, with Enhancement of Aorta and Pulmonary Artery or Radiation Exposure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: The contrast time-enhancement profiles of pulmonary artery (PA) and the aorta differ by using computed tomography (CT) angiography. Our purpose is to identify the optimal CT protocol for assessment of both vessels in one-time CT scan. Methods: The investigators prospectively enrolled 101 cases of CT angiography with suspicion of pulmonary embolism or aortic dissection in our center from 2018 to 2020. Forty cases receiving traditional two-time CT scans were collected retrospectively from 2015 to 2018. The investigators designed four groups: test bolus (TB) I, II and bolus-tracking (BT) I, II. The enhancement of the both vessels and the radiation dose of these four groups were collected. Traditional group was separated into traditional PA scan and traditional aorta scan. Data analyzed among the BT groups and the traditional groups were performed.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A practical biphasic contrast media injection protocol strongly enhances the aorta and pulmonary artery simultaneously using a single CT angiography scan.
Hsieh CC, Zeng AB, Chen CH, Jhou ZY, et al · · 2021 · cited 1× · PMID 34717585 · DOI 10.1186/s12880-021-00691-4
Verify or expand the search:
- PubMed search for NCT04832633
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04832633 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mackay Memorial Hospital
- Last refreshed: 6 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04832633.
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