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NCT07479654
AI-Enabled Frailty Risk Prediction in Adult Congenital Heart Disease
NA trial testing AI-Based Voice Emotion Detection-Guided Counselling in Adult Congenital Heart Disease in 410 participants. Not yet recruiting.
31 December 2028
Quick facts
| Lead sponsor | Mackay Memorial Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 410 |
| Start date | 1 March 2026 |
| Primary completion | 31 December 2028 |
| Estimated completion | 31 December 2028 |
Drugs / interventions tested
- AI-Based Voice Emotion Detection-Guided Counselling
- Usual Care (Control)
Conditions studied
- Adult Congenital Heart Disease — all drugs for Adult Congenital Heart Disease →
- Symptom Clusters — all drugs for Symptom Clusters →
- Frailty — all drugs for Frailty →
- Risk Prediction Model — all drugs for Risk Prediction Model →
Sponsor
Mackay Memorial Hospital
Who can join
20 and older, any sex, with Adult Congenital Heart Disease or Symptom Clusters. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this three-year mixed-methods observational study with an embedded randomized controlled trial is to develop and validate a frailty risk prediction model and evaluate an artificial intelligence-based voice emotion detection-guided counselling intervention in adults with congenital heart disease (ACHD). The main questions it aims to answer are: Are symptom clusters associated with frailty and psychological outcomes in adults with congenital heart disease? Can symptom clusters and psychosocial factors be used to predict frailty risk over time in ACHD patients? Does an AI-based voice emotion detection-guided counselling intervention improve psychological outcomes, fatigue, and quality of life among high-risk ACHD patients? Researchers will compare ACHD patients receiving AI-based voice emotion detection-guided counselling with those receiving usual care to determine whether the intervention reduces depression, anxiety, sleep disturbance, fatigue, and frailty risk, and improves grit and quality of life. Participants will: Complete longitudinal assessments of symptom clusters, frailty, and psychological status at baseline and follow-up time points Participate in qualitative interviews to explore lived experiences related to symptoms and frailty Receive AI-based voice emotion detection-guided counselling (intervention group only in Year 3)
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07479654
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT06769529 — Observational Cohort Study of Adult Patients With Congenital Heart Disease · recruiting
- NCT06784440 — Search for Noninvasive Markers of "Graft Injury" in Pediatric and Adult Patients With Congenital Heart Disease Undergoin · NA · recruiting
- NCT06932081 — Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry · recruiting
Other Mackay Memorial Hospital trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07479654 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mackay Memorial Hospital
- Last refreshed: 18 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07479654.
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