NCT04831515 is a NA clinical trial of Lens A in Astigmatism, sponsored by CooperVision, Inc..

Who is sponsoring NCT04831515?

NCT04831515 is sponsored by CooperVision, Inc..

What drugs are being tested in NCT04831515?

Interventions in NCT04831515: Lens A, Lens B.

What condition does NCT04831515 study?

NCT04831515 studies Astigmatism.

Is NCT04831515 still recruiting?

NCT04831515 is currently completed. Last updated 15 February 2022.

Are results published for NCT04831515?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2022-02-15 · How we verify

NCT04831515

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

Completed NA Results posted Last updated 15 February 2022

What this trial tests

NA trial testing Lens A in Astigmatism in 48 participants. Completed in 2 July 2021.

Timeline

29 March 2021

Primary endpoint
2 July 2021

2 July 2021

Quick facts

Lead sponsor	CooperVision, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	48
Start date	29 March 2021
Primary completion	2 July 2021
Estimated completion	2 July 2021
Sites	4 locations across United States

Drugs / interventions tested

Lens A
Lens B

Conditions studied

Astigmatism — all drugs for Astigmatism →

Sponsor

CooperVision, Inc.

Who can join

18 and older, any sex, with Astigmatism. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Overall Ease of Lens Handling Primary · 1 week

Ease of overall lens handling for putting on eyes, removing from eyes, and opening packaging will be measured on a 0-10 integer scale (0=Very difficult, 10-Very easy)

Group	Value	95% CI
Lens A	9.0	± 1.1
Lens B	8.8	± 1.5

Visual Acuity Secondary · Baseline - after lenses have settled for 10 minutes

Visual acuity will be measured using LogMAR scale in high room illumination high contrast: distance (≥4m)

Group	Value	95% CI
Lens A	-0.06	± 0.06
Lens B	-0.06	± 0.06

Visual Acuity Secondary · 1 week

Visual acuity will be measured using LogMAR scale in high room illumination high contrast: distance (≥4m)

Group	Value	95% CI
Lens A	-0.06	± 0.06
Lens B	-0.05	± 0.06

Adverse events — posted to ClinicalTrials.gov

Time frame: From dispense up to 1 week on each study lenses for a total of 2 weeks. Reporting threshold: 1%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Lens A

Serious: 0/48 (0%)

Deaths: 0/48

Lens B

Serious: 0/48 (0%)

Deaths: 0/48

Other adverse events (1 terms — click to expand)

Reaction	System	Lens A	Lens B
inferior single corneal peripheral ulcer	Eye disorders	—	—

Data from ClinicalTrials.gov NCT04831515 adverse events section.

Sponsor's own description

The objective of the study is to compare the clinical performance of two different daily disposable, SiHy toric contact lens types, Lens A and Lens B, in existing soft lens wearers when worn for one week each.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Lens A

Trials testing the same drug.

NCT05805085 — Clinical Evaluation of Hydrogel and Silicone Hydrogel Daily Disposable Toric Contact Lenses · NA · completed
NCT05688657 — Clinical Evaluation of Two Toric Contact Lenses · NA · completed
NCT05656885 — Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses · NA · completed
NCT05516082 — Clinical Evaluation of Two Daily Disposable Lenses in Sphere Design · NA · completed
NCT05457608 — Clinical Evaluation of Two Multifocal Contact Lenses · NA · completed

Other recruiting trials for Astigmatism

Currently open trials in the same condition.

NCT07303920 — Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day · NA · recruiting
NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07078799 — Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery · NA · recruiting
NCT07084844 — Patient Reported Outcomes With WaveLight Plus LASIK · recruiting
NCT07140653 — Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery · Phase 4 · recruiting

Other CooperVision, Inc. trials

Trials by the same sponsor.

NCT06817785 — Soft Lens Study: Biomedics 1 Day Extra Sphere and Clariti 1 Day Sphere · NA · completed
NCT06758076 — A Clinical Comparison of Two Soft Contact Lenses (C24-755) · NA · completed
NCT06590441 — Investigation of Wearing Compliance of Spectacles for Myopia Control · completed
NCT06609018 — Clinical Investigation of Buttermere (LENS 271) Soft Contact Lenses · NA · completed
NCT06611410 — 1 Week Crossover Study Between Two Soft Contact Lenses · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04831515 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by CooperVision, Inc.
Last refreshed: 15 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04831515.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing