Who is sponsoring NCT04828447?

NCT04828447 is sponsored by University of Florida.

What drugs are being tested in NCT04828447?

Interventions in NCT04828447: Olive Oil.

What condition does NCT04828447 study?

NCT04828447 studies Atherosclerotic Cardiovascular Disease.

Is NCT04828447 still recruiting?

NCT04828447 is currently completed. Last updated 2 August 2024.

Last reviewed 2024-08-02 · How we verify

NCT04828447

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Recipe for Heart Health

Completed NA Last updated 2 August 2024

What this trial tests

NA trial testing Olive Oil in Atherosclerotic Cardiovascular Disease in 60 participants. Completed in 1 April 2024.

Timeline

14 April 2021

Primary endpoint
22 June 2022

1 April 2024

Quick facts

Lead sponsor	University of Florida
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	other
Enrollment	60
Start date	14 April 2021
Primary completion	22 June 2022
Estimated completion	1 April 2024
Sites	1 location across United States

Drugs / interventions tested

Olive Oil — full drug profile →

Conditions studied

Atherosclerotic Cardiovascular Disease — all drugs for Atherosclerotic Cardiovascular Disease →

Sponsor

University of Florida

Who can join

Adults 18 to 100, any sex, with Atherosclerotic Cardiovascular Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall objectives of this project are to compare clinical parameters in moderate risk Atherosclerotic Cardiovascular Disease (ASCVD) patients following a Whole Food Plant Based (WFPB) diet containing a high (4 TB) compared to a low (\<1 tsp) amount of raw extra virgin olive oil.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Recipe for Heart Health: A Randomized Crossover Trial on Cardiometabolic Effects of Extra Virgin Olive Oil Within a Whole-Food Plant-Based Vegan Diet.
Krenek AM, Mathews A, Guo J, Courville AB, et al · · 2024 · cited 6× · PMID 39045758 · DOI 10.1161/jaha.124.035034
Plant-Based Culinary Medicine Intervention Improves Cooking Behaviors, Diet Quality, and Skin Carotenoid Status in Adults at Risk of Heart Disease Participating in a Randomized Crossover Trial.
Krenek AM, Aggarwal M, Chung ST, Courville AB, et al · · 2025 · cited 5× · PMID 40218890 · DOI 10.3390/nu17071132
Influence of a Virtual Plant-Based Culinary Medicine Intervention on Mood, Stress, and Quality of Life Among Patients at Risk for Cardiovascular Disease.
Krenek AM, Aggarwal M, Chung ST, Courville AB, et al · · 2025 · cited 3× · PMID 40284222 · DOI 10.3390/nu17081357

Verify or expand the search:

Other trials of Olive Oil

Trials testing the same drug.

NCT06880939 — Antarctic Krill Oil Functional Food Mitigates Bladder Cancer Treatment Side Effects · NA · not yet recruiting
NCT06880926 — Antarctic Krill Oil for Knee Osteoarthritis Pain · Phase 2 · not yet recruiting
NCT07517003 — Sunflower and Olive Oils for Preventing Diaper Dermatitis in Hospitalized Infants · NA · completed
NCT06188000 — Efficacy of Extra Virgin Olive Oil (EVOO) Supplementation on Hand-Foot Syndrome Incidence in Patients With Capecitabine · NA · unknown
NCT06677658 — The Role of Olive Oil in the Treatment of Covid-19 Pneumonia · completed

Other recruiting trials for Atherosclerotic Cardiovascular Disease

Currently open trials in the same condition.

NCT07034690 — Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dy · Phase 4 · recruiting
NCT06424860 — Fish Oil, Metformin and Heart Health in PCOS · Phase 1 · recruiting
NCT06962488 — Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure · NA · recruiting
NCT07037433 — Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiov · Phase 3 · recruiting
NCT06875973 — Pelacarsen Roll-over Extension Program · Phase 3 · recruiting

Other University of Florida trials

Trials by the same sponsor.

NCT03429413 — Maximizing HPV Vaccination: Real-time Reminders, Guidance, and Recommendations - Part 4: Feasibility Trial · NA · not yet recruiting
NCT06127550 — taVNS for Letter Learning in Dyslexia · NA · suspended
NCT07507214 — Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athl · Phase 2, PHASE3 · not yet recruiting
NCT07492316 — RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) · Phase 1 · not yet recruiting
NCT06670794 — Using Ecological Momentary Data to Inform a Web Intervention for Romantic Partners Concerned About Their Loved Ones' Dri · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04828447 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Florida
Last refreshed: 2 August 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04828447.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing