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NCT04824118: C-PLAN
Clotting Parameters After Medical Abortion
trial testing Thromboelastometry in Abortion Early in 45 participants. Completed in 12 August 2021.
12 August 2021
Quick facts
| Lead sponsor | NHS Lothian |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 45 |
| Start date | 26 March 2021 |
| Primary completion | 12 August 2021 |
| Estimated completion | 12 August 2021 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Thromboelastometry
- Clotting Studies
- Full Blood Count
- Quantitative hCG
- Pregnancy Test — full drug profile →
Conditions studied
- Abortion Early — all drugs for Abortion Early →
- Abortion, Complete — all drugs for Abortion, Complete →
- Abortion, Second Trimester — all drugs for Abortion, Second Trimester →
- Termination of Pregnancy Complicated by Embolism — all drugs for Termination of Pregnancy Complicated by Embolism →
Sponsor
NHS Lothian — full company profile →
Who can join
16 and older, female only, with Abortion Early or Abortion, Complete. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Venous thromboembolism (VTE - blood clots that form in deep veins or in the lungs) has been identified as a leading cause of death in economically developed countries for pregnant and recently-pregnant women. There is evidence that clotting parameters can take up to 6 weeks to return to normal for women who have had term deliveries, however there is an absence of information on time taken for clotting parameters to normalise following abortion. As such, existing guidelines are based solely on expert opinion and recommend durations of VTE prevention from as short as 7 days, up to 6 weeks following abortion. All women are assessed for risk of VTE, but data are needed to inform an evidence-based approach to prevention of VTE in these women. The findings from this pilot study have the potential to inform clinical guidance and possibly a larger study subsequently.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04824118
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Thromboelastometry
Trials testing the same drug.
- NCT03784794 — Patient Blood Management for Massive Obstetric Hemorrhage · NA · completed
Other recruiting trials for Abortion Early
Currently open trials in the same condition.
- NCT06787274 — Research on Equity in Abortion Care by TeleHealth · recruiting
Other NHS Lothian trials
Trials by the same sponsor.
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- NCT06932978 — The Use of Smart Glasses for Environmental Controls · NA · completed
- NCT06212622 — Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia? · completed
- NCT07049419 — The Impact of Environmental Controls on Mental Health · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04824118 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by NHS Lothian
- Last refreshed: 20 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04824118.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing