NCT04823026 (CHILD_YIC) is a clinical trial in Bacterial Infections, sponsored by Rigshospitalet, Denmark.

Who is sponsoring NCT04823026?

NCT04823026 is sponsored by Rigshospitalet, Denmark.

What condition does NCT04823026 study?

NCT04823026 studies Bacterial Infections, Urinary Tract Infections, Sepsis, Fever, Viral Infection, Infant, Newborn, Disease, Bacteremia, Meningitis.

Is NCT04823026 still recruiting?

NCT04823026 is currently completed. Last updated 28 December 2022.

Last reviewed 2022-12-28 · How we verify

NCT04823026: CHILD_YIC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Host RNA Profiles to Detect Infections in Young Infants

Completed Last updated 28 December 2022

What this trial tests

trial in Bacterial Infections in 152 participants. Completed in 31 December 2021.

Timeline

15 May 2020

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	Rigshospitalet, Denmark
Status	Completed
Study type	OBSERVATIONAL
Enrollment	152
Start date	15 May 2020
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	4 locations across Denmark

Conditions studied

Bacterial Infections — all drugs for Bacterial Infections →
Urinary Tract Infections — all drugs for Urinary Tract Infections →
Sepsis — all drugs for Sepsis →
Fever — all drugs for Fever →

Sponsor

Rigshospitalet, Denmark

Who can join

Under 3 Months, any sex, with Bacterial Infections or Urinary Tract Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study seeks to identify and test host RNA expression profiles as markers for infections in young infants. Preliminary studies have shown high sensitivity and specificity for the discrimination of bacterial from non-bacterial infections in children, but the method has only been investigated in a limited number of young infants. The study aims to include 65 young infants with serious bacterial infections. The samples will be analysed by RNA sequencing. New diagnostic tools may help reduce unnecessary antibiotic treatment, antibiotic resistance, side-effects, hospitalisation and invasive procedures.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Host RNA Expression Signatures in Young Infants with Urinary Tract Infection: A Prospective Study.
Dungu KHS, Carlsen ELM, Glenthøj JP, Schmidt LS, et al · · 2024 · cited 1× · PMID 38732074 · DOI 10.3390/ijms25094857

Verify or expand the search:

Other recruiting trials for Bacterial Infections

Currently open trials in the same condition.

NCT07017777 — A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infant · Phase 3 · recruiting
NCT07104162 — A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal I · Phase 1 · recruiting
NCT07207291 — Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers · Phase 1 · recruiting
NCT07056881 — Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa · recruiting
NCT06592586 — A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women · Phase 2, PHASE3 · active not recruiting

Other Rigshospitalet, Denmark trials

Trials by the same sponsor.

NCT07401368 — Clinicians' Trust in AI-Based Fetal Growth Estimates · NA · not yet recruiting
NCT07442357 — The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial · NA · not yet recruiting
NCT07528729 — Alcohol as a Modifiable Risk Factor for Atrial Fibrillation · NA · not yet recruiting
NCT07511439 — Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission · Phase 4 · not yet recruiting
NCT07467187 — Invasive Home Ventilation in Denmark · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04823026 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
Last refreshed: 28 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04823026.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing