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NCT07056881
Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa
trial in Osteomyelitis in 300 participants. Currently enrolling.
15 April 2026
Quick facts
| Lead sponsor | Centre Hospitalier de Saint-Denis |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 11 April 2025 |
| Primary completion | 15 April 2026 |
| Estimated completion | 15 April 2026 |
| Sites | 1 location across France |
Conditions studied
- Osteomyelitis — all drugs for Osteomyelitis →
- Pseudomonas Infections — all drugs for Pseudomonas Infections →
- Pseudomonas Aeruginosa — all drugs for Pseudomonas Aeruginosa →
- Bacterial Infections — all drugs for Bacterial Infections →
Sponsor
Centre Hospitalier de Saint-Denis
Who can join
18 and older, any sex, with Osteomyelitis or Pseudomonas Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study looks at how well one antibiotic (monotherapy) works compared to two antibiotics (combination therapy) in treating bone infections caused by Pseudomonas aeruginosa. It includes 300 adult patients who had this type of infection confirmed by lab tests and medical imaging. The goal is to find out if using just one antibiotic is as effective as using two, while also looking at side effects, the need for more surgery, antibiotic resistance, and overall antibiotic use.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07056881
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Osteomyelitis
Currently open trials in the same condition.
- NCT06283979 — A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Assoc · Phase 2 · recruiting
- NCT06526884 — Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC) · NA · active not recruiting
- NCT05713149 — Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial Agents · recruiting
- NCT03594344 — Additional Hyperbaric Oxygen After Lower Extremity Amputation · NA · recruiting
Other Centre Hospitalier de Saint-Denis trials
Trials by the same sponsor.
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- NCT07200999 — Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture · not yet recruiting
- NCT07170137 — Comparison of Uterine Distension in Hysterosonography Among Patients Monitored for Infertility · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07056881 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier de Saint-Denis
- Last refreshed: 9 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07056881.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing