Last reviewed · How we verify
NCT04810234
Neural Correlates of tVNS
trial testing transcutaneous vagal nerve stimulation (tVNS) in fMRI in 16 participants. Status unknown.
1 June 2021
Quick facts
| Lead sponsor | Maastricht University Medical Center |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 16 |
| Start date | 1 November 2020 |
| Primary completion | 1 June 2021 |
| Estimated completion | 1 June 2021 |
| Sites | 2 locations across United Kingdom, Netherlands |
Drugs / interventions tested
- transcutaneous vagal nerve stimulation (tVNS)
Conditions studied
- fMRI — all drugs for fMRI →
- Transcutaneous Vagal Nerve Stimulation (tVNS) — all drugs for Transcutaneous Vagal Nerve Stimulation (tVNS) →
- Nucleus of the Solitary Tract (NTS) — all drugs for Nucleus of the Solitary Tract (NTS) →
Sponsor
Maastricht University Medical Center
Who can join
Adults 18 to 40, female only, with fMRI or Transcutaneous Vagal Nerve Stimulation (tVNS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Transcutaneous vagal nerve stimulation (tVNS) has been applied to a number of disease areas including visceral pain, depression, cluster headache and Alzheimer's disease. However, there is marked heterogeneity in these studies pertaining to i) the anatomical site of stimulation (neck, inner concha or tragus of ear), and ii) the waveform parameters of the stimulating impulse. This exploratory cross-sectional study will address these knowledge gaps by comparative functional neuroimaging of the neural correlates of tVNS with disparate anatomical sites and electrical waveform characteristics during rest in healthy participants.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04810234
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04810234 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Maastricht University Medical Center
- Last refreshed: 22 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04810234.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing