Who is sponsoring NCT04809831?

NCT04809831 is sponsored by University of Pavia.

What drugs are being tested in NCT04809831?

Interventions in NCT04809831: Domiciliary oral care with Biorepair Peribioma Toothpaste + Mousse, Domiciliary oral care with Curasept Toothpaste (chlorhexidine 0,2%).

What condition does NCT04809831 study?

NCT04809831 studies Periodontal Diseases.

Is NCT04809831 still recruiting?

NCT04809831 is currently completed. Last updated 13 January 2022.

Last reviewed 2022-01-13 · How we verify

NCT04809831

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Use of Biorepair Peribioma Toothpaste and Mousse for Home Oral Care in Patients Undergoing Periodontal Therapy

Completed NA Last updated 13 January 2022

What this trial tests

NA trial testing Domiciliary oral care with Biorepair Peribioma Toothpaste + Mousse in Periodontal Diseases in 40 participants. Completed in 3 November 2021.

Timeline

22 March 2021

Primary endpoint
29 October 2021

3 November 2021

Quick facts

Lead sponsor	University of Pavia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	40
Start date	22 March 2021
Primary completion	29 October 2021
Estimated completion	3 November 2021
Sites	1 location across Italy

Drugs / interventions tested

Domiciliary oral care with Biorepair Peribioma Toothpaste + Mousse
Domiciliary oral care with Curasept Toothpaste (chlorhexidine 0,2%)

Conditions studied

Periodontal Diseases — all drugs for Periodontal Diseases →

Sponsor

University of Pavia

Who can join

Adults 18 to 70, any sex, with Periodontal Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a split-mouth randomized clinical trial in which a new domiciliary oral care protocol with Biorepair Peribioma Toothpaste and Mousse is evaluated in periodontal patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Paraprobiotics in Non-Surgical Periodontal Therapy: Clinical and Microbiological Aspects in a 6-Month Follow-Up Domiciliary Protocol for Oral Hygiene.
Butera A, Gallo S, Pascadopoli M, Maiorani C, et al · · 2022 · cited 75× · PMID 35208792 · DOI 10.3390/microorganisms10020337

Verify or expand the search:

Other recruiting trials for Periodontal Diseases

Currently open trials in the same condition.

NCT07358104 — Efficacy of Camel Whey Protein and Camel Whey Protein Nanoparticles for Treating Intra-bony Periodontal Defects · NA · active not recruiting
NCT07312045 — HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical T · recruiting
NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting

Other University of Pavia trials

Trials by the same sponsor.

NCT07491536 — Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis · NA · recruiting
NCT07421128 — The Pause, Learn, and Activate Yourself (PLAY) · NA · not yet recruiting
NCT07199712 — Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy · NA · completed
NCT07088653 — Comparison of 0.12% Chlorhexidine and MicroRepair ABX Mouthwash in Gingivitis Management · NA · completed
NCT07140146 — Trehalose vs Glycine Air-Polishing in Peri-Implant Mucositis Treatment · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04809831 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pavia
Last refreshed: 13 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04809831.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing