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NCT04804839
Comparison of the Effectiveness of Different Conservative Treatment Protocols in Postprostatectomy Urinary Incontinence
NA trial testing First research arm in Urinary Incontinence in 72 participants. Completed in 1 March 2022.
1 March 2022
Quick facts
| Lead sponsor | Hacettepe University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 1 April 2021 |
| Primary completion | 1 March 2022 |
| Estimated completion | 1 March 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- First research arm
- Second research arm
- Third research arm
Conditions studied
- Urinary Incontinence — all drugs for Urinary Incontinence →
- Prostate Cancer — all drugs for Prostate Cancer →
- Urinary Incontinence,Stress — all drugs for Urinary Incontinence,Stress →
- Urinary Incontinence Due to Urethral Sphincter Incompetence — all drugs for Urinary Incontinence Due to Urethral Sphincter Incompetence →
Sponsor
Hacettepe University
Who can join
18 and older, male only, with Urinary Incontinence or Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main purpose of this study is to reveal the effectiveness of the Knack maneuver and lifestyle recommendations program to be given in addition to the pelvic floor muscle training (PFMT) program, which has been proven to be effective in individuals with urinary incontinence symptoms after prostatectomy. This study is a prospective, controlled, randomized clinical trial. The study includes an 8-week pelvic floor muscle training, Knack maneuver and lifestyle recommendations. In summary, it is stated in the literature that PFMT and lifestyle recommendations are beneficial in the treatment of urinary incontinence (UI). However, although there is evidence of the effectiveness of the Knack maneuver in stress UI in women, there is no evidence of the Knack maneuver in urinary incontinence after prostatectomy. On the other hand, the literature on the effect of lifestyle recommendations after prostatectomy is very limited. Therefore, the aim of this study is to reveal the effectiveness of the Knack maneuver and lifestyle recommendations program, which will be given in addition to the PFMT program, which has been demonstrated in individuals with UI complaints after radical prostatectomy, in a randomized controlled design.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Lifestyle recommendations and pelvic floor muscle training with Knack maneuver for post-prostatectomy urinary incontinence: a randomized controlled trial.
Gerlegiz ENA, Akbayrak T, Gürşen C, Yazici MS, et al · · 2025 · cited 1× · PMID 39888446 · DOI 10.1007/s00520-025-09197-z
Verify or expand the search:
- PubMed search for NCT04804839
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04804839 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hacettepe University
- Last refreshed: 26 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04804839.
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