NCT04794712

Evaluation of Pain Associated With Chronic Venous Insufficiency

Status unknown Last updated 12 March 2021

What this trial tests

trial testing Venous reflux tools (Ultrasound and Photo plethysmography (PPG)) in Chronic Venous Insufficiency in 80 participants. Status unknown.

Timeline

15 May 2021

Primary endpoint
14 May 2022

14 May 2022

Quick facts

Lead sponsor	Imperial College London
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	80
Start date	15 May 2021
Primary completion	14 May 2022
Estimated completion	14 May 2022
Sites	1 location across United Kingdom

Drugs / interventions tested

• Venous reflux tools (Ultrasound and Photo plethysmography (PPG))

Conditions studied

• Chronic Venous Insufficiency — all drugs for Chronic Venous Insufficiency →
• Varicose Veins of Lower Limb — all drugs for Varicose Veins of Lower Limb →

Sponsor

Imperial College London

Who can join

18 and older, any sex, with Chronic Venous Insufficiency or Varicose Veins of Lower Limb. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic venous insufficiency occurs when your leg veins don't allow blood to flow back up to your heart. Normally, the valves in your veins make sure that blood flows toward your heart. But when these valves don't work well, blood can also flow backwards. This can cause blood to collect (pool) in the legs. Chronic venous disease is a highly prevalent condition in the general population, and it has a significant impact on quality of life. While it is usually manifested by obvious signs, such as varicose veins and venous ulcers, other symptoms of the disease are less specific. Among the other symptoms, which include heaviness, swelling, muscle cramps and restless legs, pain is the symptom that most frequently compels CVeD patients to seek medical aid. However, there is a substantial discrepancy between pain severity and clinically detectable signs of CVeD, questioned by several opposing studies. Further evaluation is needed to clarify this subject, and to analyse whether pain development predicts objective tool to evaluate pain by dosflexin exercise pre surgery and post and measure the severity of pain by heat stimulation . General management of CVeD starts with advising lifestyle . pain in chronic venous insufficiency it will measure before and after treatment by using contact heat evoked potential (CHEPS) and visual dialog scale ( VAS ) to estimate the pain intensity the severity of the pain before the patient do exercise before three moths of leaser endovenous ablation procedure . 2-photo-plethysomography Non invasive technique , pp sensor emit infrared light detects changes in reflection from epiderma layer . Vessels full of blood reflect 10 times less than without blood . On dorsiflexion - pressure drops, increasing reflection in the measuring window Venous assessment the venous refill time, is shorter and typically less than 20 s

Publications & conference data

No peer-reviewed publications indexed yet for this trial.