NCT04794621 (EDT BioFilm) is a NA clinical trial of Electroceutical Dressing Technology-EDThi in Wound Heal, sponsored by Indiana University.

Who is sponsoring NCT04794621?

NCT04794621 is sponsored by Indiana University.

What drugs are being tested in NCT04794621?

Interventions in NCT04794621: Electroceutical Dressing Technology-EDThi, Adding EDTlo (Procellera®) for 3 weeks after use of EDThi.

What condition does NCT04794621 study?

NCT04794621 studies Wound Heal.

Is NCT04794621 still recruiting?

NCT04794621 is currently completed. Last updated 3 October 2023.

Last reviewed 2023-10-03 · How we verify

NCT04794621: EDT BioFilm

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Electroceutical Dressing Technology (EDT) Against Wound Microbial Biofilm Infection

Completed NA Last updated 3 October 2023

What this trial tests

NA trial testing Electroceutical Dressing Technology-EDThi in Wound Heal in 112 participants. Completed in 7 July 2023.

Timeline

3 June 2021

Primary endpoint
7 July 2023

7 July 2023

Quick facts

Lead sponsor	Indiana University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	112
Start date	3 June 2021
Primary completion	7 July 2023
Estimated completion	7 July 2023
Sites	3 locations across United States

Drugs / interventions tested

Electroceutical Dressing Technology-EDThi
Adding EDTlo (Procellera®) for 3 weeks after use of EDThi

Conditions studied

Wound Heal — all drugs for Wound Heal →

Sponsor

Indiana University

Who can join

18 and older, any sex, with Wound Heal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There are currently limited treatments available that show anti-biofilm efficacy for wound infection management Biofilms account for over 80% of infections and approximately 65% of nosocomial infections caused by microorganisms in the developed world involve biofilms. There clearly is a need for cost effective, highly stable, easily obtained biofilm targeted strategies for treatment of chronic wound biofilm infections. The information generated from this project has the potential of providing considerable benefits to wound care by determining the efficacy of EDT dressing in managing wound biofilm infection and efficacy in wound healing and closure. Such knowledge could help therapeutic strategies and could provide information for future clinical studies to further understanding -of EDT wound dressings.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Recent Advances in Functional Wound Dressings.
Tran HQ, Shahriar SMS, Yan Z, Xie J. · · 2023 · cited 28× · PMID 36301918 · DOI 10.1089/wound.2022.0059
Novel Diagnostic Technologies and Therapeutic Approaches Targeting Chronic Wound Biofilms and Microbiota.
Chen V, Burgess JL, Verpile R, Tomic-Canic M, et al · · 2022 · cited 18× · PMID 37007641 · DOI 10.1007/s13671-022-00354-9
A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound Biofilm Infection.
Chan RK, Nuutila K, Mathew-Steiner SS, Diaz V, et al · · 2024 · cited 11× · PMID 36855334 · DOI 10.1089/wound.2023.0007
Electrochemical Devices in Cutaneous Wound Healing.
Evans JP, Sen CK. · · 2023 · cited 8× · PMID 37370642 · DOI 10.3390/bioengineering10060711

Verify or expand the search:

Other recruiting trials for Wound Heal

Currently open trials in the same condition.

NCT07261501 — An Exploratory Research on the Efficacy and Safety of Antibacterial Absorbable Dressing in Chronic Non-healing Wounds · NA · recruiting
NCT07209358 — EDX110 Randomized Control Trial for Treatment of DFUs · NA · recruiting
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NCT06841237 — Randomized Controlled Trial on the Efficacy and Safety of Xiang Lei Ointment in Diabetic-related Ulcer Management · NA · recruiting
NCT06563323 — Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG) · Phase 2 · recruiting

Other Indiana University trials

Trials by the same sponsor.

NCT07470086 — The Role of Environmental Temperatures in Respiratory Control · NA · not yet recruiting
NCT07470099 — The Role of Breathing Perception in Respiratory Control · NA · not yet recruiting
NCT07179952 — Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) · Phase 2 · not yet recruiting
NCT07070804 — Maternal Biomarkers and Environmental Contributors to Autism Spectrum Disorders in Children of First-time Mothers · not yet recruiting
NCT07499583 — Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, PHASE2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04794621 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indiana University
Last refreshed: 3 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04794621.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing