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NCT04793529

Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study

Completed NA Last updated 27 July 2023
What this trial tests

NA trial testing Cholecalciferol in Verruca Vulgaris in 60 participants. Completed in 1 October 2019.

Timeline
1 January 2019
Primary endpoint
1 October 2019
1 October 2019

Quick facts

Lead sponsorBenha University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment60
Start date1 January 2019
Primary completion1 October 2019
Estimated completion1 October 2019
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Benha University

Who can join

Adults 18 to 45, any sex, with Verruca Vulgaris or Involucrin. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Vitamin D3 plays important role in keratinocyte differentiation and had been used recently in verruca vulgaris. Aim of the work: To assess the expression of involucrin in verrucae vulgaris before and after injection of vitamin D3. Subjects and Methods: This study included 60 patients with verrucae vulgaris subjected to intralesional injection of vitamin D3 at three weeks interval for a maximum of five sessions. Immunohistochemical assessment of involucrin was done before and after injection and compared to skin biopsies from 30 healthy individuals

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Does involucrin have a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study.
    Akl EM, Sorour NE, Abdou AG, Elesawy FM. · · 2021 · PMID 35068499 · DOI 10.4103/ijd.ijd_808_20

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Other trials of Cholecalciferol

Trials testing the same drug.

Other Benha University trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04793529.

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