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NCT04793529
Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study
NA trial testing Cholecalciferol in Verruca Vulgaris in 60 participants. Completed in 1 October 2019.
1 October 2019
Quick facts
| Lead sponsor | Benha University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 January 2019 |
| Primary completion | 1 October 2019 |
| Estimated completion | 1 October 2019 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Cholecalciferol (cholecalciferol) — full drug profile →
Conditions studied
- Verruca Vulgaris — all drugs for Verruca Vulgaris →
- Involucrin — all drugs for Involucrin →
Sponsor
Benha University
Who can join
Adults 18 to 45, any sex, with Verruca Vulgaris or Involucrin. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Vitamin D3 plays important role in keratinocyte differentiation and had been used recently in verruca vulgaris. Aim of the work: To assess the expression of involucrin in verrucae vulgaris before and after injection of vitamin D3. Subjects and Methods: This study included 60 patients with verrucae vulgaris subjected to intralesional injection of vitamin D3 at three weeks interval for a maximum of five sessions. Immunohistochemical assessment of involucrin was done before and after injection and compared to skin biopsies from 30 healthy individuals
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Does involucrin have a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study.
Akl EM, Sorour NE, Abdou AG, Elesawy FM. · · 2021 · PMID 35068499 · DOI 10.4103/ijd.ijd_808_20
Verify or expand the search:
- PubMed search for NCT04793529
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04793529 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Benha University
- Last refreshed: 27 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04793529.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing