Last reviewed 2026-04-20 · How we verify

Vitamin D3 (cholecalciferol)

At a glance

Approved indications

• Glucocorticoid Induced Osteoporosis
• Hypocalcemia
• Hypogonadal Osteoporosis in Males
• Hypoparathyroidism
• Osteomalacia
• Osteoporosis
• Postmenopausal osteoporosis
• Prevention of dental caries
• Rickets
• Vitamin D Dependent Rickets
• Vitamin D deficiency
• Vitamin deficiency

Boxed warnings

• WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Common side effects

No common side effects on file.

Key clinical trials

• Clinical Effectiveness of Calcipotriene in Acute Graft Versus Host Disease of the Skin: A Pilot Study (NA)
• School-Based Assessment of Micronutrient Interventions in Adolescents (SAMIA) in Zanzibar (NA)
• Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Including Diversity and Stress Determinants, Among Veterans (Phase 2)
• A Randomized, Open-label, Single-dose Study to Evaluate the Safety and the Pharmacokinetics After Oral Concurrent Administration of HDDO-16141 and HDDO-16142 in Healthy Adult Subjects (Phase 1)
• Vitamin D and the Free Hormone Hypothesis: Lessons From Surgical Stress (N/A)
• Skeletal Muscle Strength Including Its Energy Metabolism, Bone Mineral Homeostasis and Th1/Th2 Cytokines Expression in Asian Indians With Chronic Hypovitaminosis D Before and After Oral Cholecalcifero (Phase 1)
• Randomized Clinical Trial for The Evaluation of The Effects Of Cholecalciferol Supplementation On The Parathyroid Hormone In Hemodialysis Patients (Phase 4)
• Analysis of Some Heavy Metals and Some Vitamins Levels in Maternal Samples, Fetal Samples and Breast Milk for Fetal Growth Restriction. (N/A)

Primary sources

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