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NCT04791202
Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis
Phase 3 trial testing Dextrose in Pain in 130 participants. Status unknown.
1 March 2022
Quick facts
| Lead sponsor | Christine M. Kleinert Institute for Hand and Microsurgery |
|---|---|
| Phase | Phase 3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 130 |
| Start date | 1 April 2021 |
| Primary completion | 1 March 2022 |
| Estimated completion | 1 July 2022 |
Drugs / interventions tested
- Dextrose — full drug profile →
- Methylprednisolone Acetate 40 MG/ML — full drug profile →
Conditions studied
- Pain — all drugs for Pain →
- Satisfaction, Patient — all drugs for Satisfaction, Patient →
- Functionality — all drugs for Functionality →
Sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Who can join
18 and older, any sex, with Pain or Satisfaction, Patient. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The evolving reports form recent studies are creating a promise on the potential use of dextrose injections for treating arthritis and replacing current method of treating early osteoarthritis by corticosteroids by giving long standing effect and improving patients' symptoms and function. Over the past 5 years, an increasing number of level I and level II studies have emerged, examining the effect of intra-articular prolotherapy for the treatment of both hip and knee osteoarthritis. On the contrary, there is limited data in small joints, such as the temporomandibular joint.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04791202
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Christine M. Kleinert Institute for Hand and Microsurgery trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04791202 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Christine M. Kleinert Institute for Hand and Microsurgery
- Last refreshed: 16 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04791202.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing