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NCT04784260
Microbiome Influence on Seminal Quality
trial testing Microbiome analysis in Infertility, Male in 40 participants. Completed in 10 March 2023.
12 January 2023
Quick facts
| Lead sponsor | Instituto Valenciano de Infertilidad, IVI Alicante |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 1 June 2020 |
| Primary completion | 12 January 2023 |
| Estimated completion | 10 March 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Microbiome analysis
Conditions studied
- Infertility, Male — all drugs for Infertility, Male →
Sponsor
Instituto Valenciano de Infertilidad, IVI Alicante — full company profile →
Who can join
Adults 18 to 35, male only, with Infertility, Male. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The microbiome plays an important role in health and in some unknown etiologies. Some previous studies have identified bacteria in semen as a potential factor in male infertility. More studies are needed to discover associations between microbiomes and semen quality. In this study, forty semen samples from donors candidates will be collected where clinical criteria for seminal quality (volume, concentration, motility and morphology) will be measured and bacterial communities examined. With the next-generation sequencing of gene technology and bioinformatic analysis, we can investigate the associations between bacterial communities and seminal quality. It would be interesting to know if the proportion of certain bacteria is significantly higher in samples of normal seminal quality or significantly higher in samples of low seminal quality. This study could contribute to the current understanding of certain etiologies of male fertility.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04784260
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Microbiome analysis
Trials testing the same drug.
- NCT04725123 — Addressing Personalized Needs in Clostridioides Difficile Infection · NA · completed
- NCT04168567 — The Impact of Body Mass Index on the Endometrial Microbiome in IVF Treatments. Tampere Infertility Microbiome Project (T · completed
- NCT03688347 — Microbiome in Lung Cancer and Other Malignancies · completed
Other recruiting trials for Infertility, Male
Currently open trials in the same condition.
- NCT06950203 — The Effect of Supplementation With Fish Oil (EPAX EVOLVE 05) on Sperm Quality · NA · recruiting
- NCT06539585 — Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality · NA · active not recruiting
- NCT05514223 — Measuring Free Radicals in Human Sperm Cells Related to Microbiota and Lifestyle Factors · recruiting
- NCT06841861 — Spermatogonial Differentiation Via Testicular Organoid · Phase 1, PHASE2 · recruiting
- NCT05903859 — Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI) · Phase 3 · recruiting
Other Instituto Valenciano de Infertilidad, IVI Alicante trials
Trials by the same sponsor.
- NCT07504575 — Effect of PRP in Donor Semen During Cryoprervation · recruiting
- NCT03741699 — Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH) · Phase 3 · completed
- NCT02527954 — Aneuploidies in Embryos and Spermatozoa From Patients With Y-chromosome Microdeletions · terminated
- NCT02535377 — Human Sperm Markers of Cryodamage Resistance · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04784260 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto Valenciano de Infertilidad, IVI Alicante
- Last refreshed: 13 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04784260.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing