NCT04775459 (ECHOSURF) is a clinical trial of Surfactant administration until 2020 in Preterm Birth, sponsored by Centre Hospitalier Universitaire de Saint Etienne.

Who is sponsoring NCT04775459?

NCT04775459 is sponsored by Centre Hospitalier Universitaire de Saint Etienne.

What drugs are being tested in NCT04775459?

Interventions in NCT04775459: Surfactant administration until 2020, Surfactant administration since 2021.

What condition does NCT04775459 study?

NCT04775459 studies Preterm Birth.

Is NCT04775459 still recruiting?

NCT04775459 is currently completed. Last updated 21 June 2024.

Last reviewed 2024-06-21 · How we verify

NCT04775459: ECHOSURF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Surfactant Replacement Guided by Early Lung Ultrasound Score in Preterm Newborns With Respiratory Distress Syndrome

Completed Last updated 21 June 2024

What this trial tests

trial testing Surfactant administration until 2020 in Preterm Birth in 84 participants. Completed in 31 May 2021.

Timeline

1 January 2021

Primary endpoint
31 May 2021

31 May 2021

Quick facts

Lead sponsor	Centre Hospitalier Universitaire de Saint Etienne
Status	Completed
Study type	OBSERVATIONAL
Enrollment	84
Start date	1 January 2021
Primary completion	31 May 2021
Estimated completion	31 May 2021
Sites	1 location across France

Drugs / interventions tested

Surfactant administration until 2020 — full drug profile →
Surfactant administration since 2021 — full drug profile →

Conditions studied

Preterm Birth — all drugs for Preterm Birth →

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Who can join

Under 1 Day, any sex, with Preterm Birth. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Lung immaturity is a major issue in neonatal unit.The surfactant administration improves the pulmonary prognosis in premature infants with hyaline membrane disease who escape continuous positive airway pressure (CPAP). This surfactant had been administered at 5h25min of life in Saint Etienne from 2016 to 2019. Studies suggest that the earlier the surfactant is administered, the more it can reduce the rate of bronchodysplasia and mortality. And some studies show a pulmonary ultrasound could help to administrate the surfactant earlier This is why a new faster strategy for diagnosing preterms needing surfactant will be usefulness and have been done in Saint-Etienne since 2021 thanks to a ultrasound score (LUS).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Surfactant therapy guided by tests for lung maturity in preterm infants at risk of respiratory distress syndrome.
Sibrecht G, Kearl CR, Borys F, Morariu M, et al · · 2023 · cited 5× · PMID 37882216 · DOI 10.1002/14651858.cd013158.pub2

Verify or expand the search:

Other recruiting trials for Preterm Birth

Currently open trials in the same condition.

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Other Centre Hospitalier Universitaire de Saint Etienne trials

Trials by the same sponsor.

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NCT07483710 — Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission an · NA · not yet recruiting
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NCT07344298 — Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04775459 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Saint Etienne
Last refreshed: 21 June 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04775459.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing