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NCT04731168: PoMAD
Prevention of Sleep Apnea After General Anaesthesia With a MAD
NA trial testing Mandibular advancement device in Peri-operative Medicine in 100 participants. Completed in 31 October 2023.
31 October 2023
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire Vaudois |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 1 February 2021 |
| Primary completion | 31 October 2023 |
| Estimated completion | 31 October 2023 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Mandibular advancement device
Conditions studied
- Peri-operative Medicine — all drugs for Peri-operative Medicine →
- Sleep Apnea — all drugs for Sleep Apnea →
Sponsor
Centre Hospitalier Universitaire Vaudois
Who can join
18 and older, any sex, with Peri-operative Medicine or Sleep Apnea. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sleep apneic episodes increase after general anaesthesia up to the third postoperative night. A mandibular advancement device, called MAD, is a small device that is inserted in the patient's mouth during the night and allows the advancement of the mandible, preventing sleep apneic episodes. The objective of this randomized controlled trial is to determine whether a MAD reduces the impact of general anaesthesia on the increase of the sleep apneic episodes in the postoperative period. All patients will have their sleep-related respiratory data measured using a portable respiratory polygraphy recorder (ResMed Embletta® system). This portable recorder allows a non-invasive recording of nasal airflow through a nasal cannula, oxygen saturation (SpO2) via finger pulse oximetry, respiratory efforts through thoracic and abdominal belts, and body position.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04731168
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mandibular advancement device
Trials testing the same drug.
- NCT07460505 — Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure · NA · not yet recruiting
- NCT06103630 — Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device · NA · recruiting
- NCT07003854 — Effects of Mandibular Advancing Device in Obstructive Sleep Apnea · NA · completed
- NCT02948894 — Mandibular Advancement Device for Treatment of Obstructive Sleep Apnea and Its Impact on Cardiac Remodeling · Phase 2, PHASE3 · unknown
Other Centre Hospitalier Universitaire Vaudois trials
Trials by the same sponsor.
- NCT07427511 — SwissNeuroRehab - HDHI · NA · recruiting
- NCT07263438 — Efficacy of the Combination of Trimipramine and Atezolizumab With Bevacizumab in Patients With Recurrent Glioblastoma: a · Phase 2 · recruiting
- NCT07139756 — Deciphering the Mechanisms of Central BP Regulation in Patients With PD Associated With Orthostatic Hypotension · not yet recruiting
- NCT07109388 — Comparison of Pericapsular Nerve Group (PENG) Block With a Combined Femoral, Sciatic, Lateral Femoral Cutaneous Nerve Bl · NA · not yet recruiting
- NCT07268378 — Supervision of Clinicians in Oncology by Psycho-oncologists : Evaluation · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04731168 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire Vaudois
- Last refreshed: 21 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04731168.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing