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NCT04701671
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
trial testing Observational (not including MRI scanning) in Pediatric Obesity in 180 participants. Currently enrolling.
9 May 2028
Quick facts
| Lead sponsor | University of Pittsburgh |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 180 |
| Start date | 10 December 2020 |
| Primary completion | 9 May 2028 |
| Estimated completion | 9 May 2028 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Observational (not including MRI scanning)
- Observational (including MRI scanning)
Conditions studied
- Pediatric Obesity — all drugs for Pediatric Obesity →
- Binge-Eating Disorder — all drugs for Binge-Eating Disorder →
Sponsor
University of Pittsburgh
Who can join
Adults 9 to 12, any sex, with Pediatric Obesity or Binge-Eating Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and psychosocial health complications. Although our recently published data suggest that youth with these conditions may have relative deficits in neurocognitive functioning, particularly working memory, understanding of how these processes and their neural correlates are related to change and stability in eating and weight-related outcomes over time is limited, thereby impeding development of targeted, optimally timed interventions. The present study aims to assess prospective associations between general and food-specific executive functioning and underlying neural substrates, and eating and weight outcomes among children at varying levels of risk overweight/obesity and eating disorders, which will help guide research efforts towards the development of effective prevention and intervention strategies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04701671
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Pittsburgh trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04701671 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pittsburgh
- Last refreshed: 10 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04701671.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing