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NCT04679961
Deep Learning on 3D Cellular-resolution Tomogram
trial testing ApolloVue® S100 Image System (Apollo Medical Optics) in Skin Diseases in 107 participants. Completed in 14 December 2022.
14 December 2022
Quick facts
| Lead sponsor | Mackay Memorial Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 107 |
| Start date | 21 December 2020 |
| Primary completion | 14 December 2022 |
| Estimated completion | 14 December 2022 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- ApolloVue® S100 Image System (Apollo Medical Optics)
Conditions studied
- Skin Diseases — all drugs for Skin Diseases →
Sponsor
Mackay Memorial Hospital
Who can join
20 and older, any sex, with Skin Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Skin biopsy is the main method to diagnose skin tumors, skin inflammation, and pigmented diseases. However, biopsy is an invasive method that can cause wounds and scars. Optical coherent tomography (OCT) technology is a fast, non-invasive, non-radioactive, and label-free imaging method. This technology generates real-time images of living tissue by detecting the variations in the refractive indexes of various components in soft tissues. Recently, there is a breakthrough progress that the newly designed ultrahigh resolution OCT can provide in vivo cellular resolution similar to histopathological sections in the high magnification. In our previous clinical trial "Early feasibility study: application of OCT imaging in dermatology" (approved by IRB of MacKay Memorial Hospital, no. 17CT062Be), it showed characteristic features of different skin inflammatory diseases and tumors can be distinguished successfully in tomograms. There were no adverse event or serious adverse event in this trial. Artificial intelligence technologies have been used widely in the image analysis in recent years. Hence, we aim to collect OCT tomograms of common skin inflammatory diseases, skin tumors, and pigmented diseases, and compare with normal skin for machine learning. We expect the integration of tomograms with deep learning artificial intelligence may assist identifying histological features in these images and provide new alternative way for non-invasive diagnosis in dermatology.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04679961
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Related trials
Other trials of ApolloVue® S100 Image System (Apollo Medical Optics)
Trials testing the same drug.
- NCT04935424 — Evaluation of Treatment for Leukoderma by Cellular Level Resolution Full-field Optical Coherence Tomography · completed
Other recruiting trials for Skin Diseases
Currently open trials in the same condition.
- NCT07412691 — A Study to Evaluate the Safety of BG-A3004 in Healthy Participants and Patients With Immune-Mediated Skin Diseases · Phase 1 · recruiting
- NCT07091604 — An Observational Study to Assess Objective Skin Pigmentation Variation. · recruiting
- NCT07158879 — Skin Reactions Related to Thoracic Implantable Chamber Dressings · recruiting
- NCT06850311 — Herbal Ointment in Treating Atopic Dermatitis Topically · Phase 2, PHASE3 · recruiting
- NCT06563323 — Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG) · Phase 2 · recruiting
Other Mackay Memorial Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04679961 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mackay Memorial Hospital
- Last refreshed: 17 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04679961.
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