NCT04667884 is a NA clinical trial of Prebiotics or Probiotics in Constipation, sponsored by Xi'an Jiaotong University.

Who is sponsoring NCT04667884?

NCT04667884 is sponsored by Xi'an Jiaotong University.

What drugs are being tested in NCT04667884?

Interventions in NCT04667884: Prebiotics or Probiotics.

What condition does NCT04667884 study?

NCT04667884 studies Constipation.

Is NCT04667884 still recruiting?

NCT04667884 is currently completed. Last updated 14 October 2021.

Last reviewed 2021-10-14 · How we verify

NCT04667884

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation

Completed NA Last updated 14 October 2021

What this trial tests

NA trial testing Prebiotics or Probiotics in Constipation in 250 participants. Completed in 30 September 2021.

Timeline

15 August 2020

Primary endpoint
22 May 2021

30 September 2021

Quick facts

Lead sponsor	Xi'an Jiaotong University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	250
Start date	15 August 2020
Primary completion	22 May 2021
Estimated completion	30 September 2021
Sites	1 location across China

Drugs / interventions tested

Prebiotics or Probiotics

Conditions studied

Constipation — all drugs for Constipation →

Sponsor

Xi'an Jiaotong University

Who can join

Adults 18 to 70, any sex, with Constipation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study intends to evaluate the effects of three prebiotic solid beverages (mainly dietary fiber and prebiotics) and one probiotic solid beverage on the laxative effect of patients with functional constipation through randomized controlled trials. The influence of tract flora is expected to provide a basis for related therapies for patients with functional constipation.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial.
Lai H, Li Y, He Y, Chen F, et al · · 2023 · cited 134× · PMID 37078654 · DOI 10.1080/19490976.2023.2197837
Recent advances in therapeutic probiotics: insights from human trials.
Cho M-Y, Eom J-H, Choi E-M, Yang S-J, et al · · 2025 · cited 17× · PMID 40261032 · DOI 10.1128/cmr.00240-24

Verify or expand the search:

Other recruiting trials for Constipation

Currently open trials in the same condition.

NCT07462481 — Probiotic Improve Constipation · NA · recruiting
NCT07466914 — Constipation in Children With Cerebral Palsy · active not recruiting
NCT07215351 — Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women · NA · recruiting
NCT07135362 — The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement · NA · recruiting
NCT07091084 — A Study of Herbal Supplements in Cancer Survivors With Constipation · NA · recruiting

Other Xi'an Jiaotong University trials

Trials by the same sponsor.

NCT06824493 — Orthodontic Treatment on Oral Microbiota and Salivary Proteins · not yet recruiting
NCT06885658 — Effectiveness of Visual Storytelling Intervention on Antibiotic Adherence in UTI Patients · NA · completed
NCT05606263 — Efficacy and Safety of Caldonirimab Plus Nimotuzumab for Recurrent or Metastatic Cervical Cancer · Phase 2 · unknown
NCT05718765 — The Effect of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients · NA · completed
NCT05427422 — Stroke Recovery Research Based on EEG-fMRI · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04667884 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Xi'an Jiaotong University
Last refreshed: 14 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04667884.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing