Last reviewed · How we verify
NCT06824493
Orthodontic Treatment on Oral Microbiota and Salivary Proteins
trial testing no interventions in Orthodontics in 150 participants. Not yet recruiting.
1 March 2027
Quick facts
| Lead sponsor | Xi'an Jiaotong University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 1 July 2025 |
| Primary completion | 1 March 2027 |
| Estimated completion | 1 September 2027 |
Drugs / interventions tested
- no interventions — full drug profile →
- None-placebo — full drug profile →
- No Intervention: Observational Cohort — full drug profile →
Conditions studied
- Orthodontics — all drugs for Orthodontics →
- White Spot Lesions [Initial Caries] on Smooth Surface of Tooth — all drugs for White Spot Lesions [Initial Caries] on Smooth Surface of Tooth →
- Caries, Dental — all drugs for Caries, Dental →
Sponsor
Xi'an Jiaotong University
Who can join
Adults 6 to 18, any sex, with Orthodontics or White Spot Lesions [Initial Caries] on Smooth Surface of Tooth. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Study on the changes in oral microbiota during orthodontic treatment in patients aged 8-18 years. Orthodontic patients treated at Stomatology Hospital of Xi'an Jiaotong University from March 2025 to March 2027 will be recruited. Prior to orthodontic treatment, routine preoperative examinations will be conducted, informed consent forms will be signed, baseline oral conditions will be recorded, and oral and psychological-related questionnaires will be completed. Patients will be informed of the need for regular oral hygiene check-ups, caries risk assessments will be performed, and plaque, saliva, and intraoral photographs will be collected. During orthodontic treatment, plaque samples will be collected every 3 months, and saliva samples will be collected every 6 months until the treatment is completed to evaluate the changes in oral microbiota throughout the orthodontic process.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06824493
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06824493 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xi'an Jiaotong University
- Last refreshed: 4 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06824493.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing