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NCT04632277: Mg

Is Mg do Improve the Glycemic Control in Patients Drink a Desalinate Water

Completed NA Last updated 29 September 2021
What this trial tests

NA trial testing Water in Diabetes Mellitus in 102 participants. Completed in 1 August 2021.

Timeline
25 August 2020
Primary endpoint
1 May 2021
1 August 2021

Quick facts

Lead sponsorImam Abdulrahman Bin Faisal University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposeprevention
Enrollment102
Start date25 August 2020
Primary completion1 May 2021
Estimated completion1 August 2021
Sites2 locations across Saudi Arabia

Drugs / interventions tested

Conditions studied

Sponsor

Imam Abdulrahman Bin Faisal University

Who can join

Adults 20 to 85, any sex, with Diabetes Mellitus or Patients. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background and aim: Diabetes mellitus as a chronic disease is on rise on parallel with diseases. Magnesium (Mg) supplementation may help control glycemic response among type 2 diabetes (T2D) patients. We aim to present an overview of the possible influence of drinking water in general and mineral water in particular in improving glycemic parameters in persons with type 2 diabetes. Method: A randomized double blind controlled clinical trial will be conducted at the Endocrine clinic (KFHU) on 900 of patients with T2DM. All subjects participated in this study will be randomly allotted into three groups (each group N=300) to which the three waters were supplied in similar bottles marked A "tap water", B "bottle water" and C "control without any intervention". Blood samples will be taken before and after the intervention to determine the serum concentration of magnesium, Calcium, Vit D, creatinine, FBS, serum Ca, HbA1c, fasting C-peptide levels, fasting insulin levels and insulin sensitivity. Magnesium and calcium levels in urine will be expressed as the creatinine ratio

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Beneficial effects of adding magnesium to desalinated drinking water on metabolic and insulin resistance parameters among patients with type 2 diabetes mellitus: a randomized controlled clinical trial.
    Albaker WI, Al-Hariri MT, Al Elq AH, Alomair NA, et al · · 2022 · cited 8× · PMID 36408199 · DOI 10.1038/s41545-022-00207-9

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