Last reviewed · How we verify
NCT04632095: PASTA
Parasternal vs. Sternotomy Approach for Conventional Aortic Valve Replacement
NA trial testing Aortic valve replacement due to sternotomy in Aortic Valve Stenosis in 50 participants. Status unknown.
16 March 2022
Quick facts
| Lead sponsor | Jena University Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 16 March 2021 |
| Primary completion | 16 March 2022 |
| Estimated completion | 15 November 2022 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Aortic valve replacement due to sternotomy
- Aortic valve replacement due to parasternal right anterior mini-thoracotomy
Conditions studied
- Aortic Valve Stenosis — all drugs for Aortic Valve Stenosis →
Sponsor
Jena University Hospital
Who can join
18 and older, any sex, with Aortic Valve Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective randomized study comparing aortic valve replacement using parasternal or sternotomy access with regard to quality of life and systemic inflammatory reaction.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults.
Abbasciano RG, Tomassini S, Roman MA, Rizzello A, et al · · 2023 · cited 7× · PMID 37873947 · DOI 10.1002/14651858.cd013584.pub2
Verify or expand the search:
- PubMed search for NCT04632095
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04632095 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jena University Hospital
- Last refreshed: 23 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04632095.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing