NCT04630535 is a clinical trial of aorto-bifemoral bypass surgery in Obstructive Sleep Apnea, sponsored by St. Anne's University Hospital Brno, Czech Republic.

Who is sponsoring NCT04630535?

NCT04630535 is sponsored by St. Anne's University Hospital Brno, Czech Republic.

What drugs are being tested in NCT04630535?

Interventions in NCT04630535: aorto-bifemoral bypass surgery.

What condition does NCT04630535 study?

NCT04630535 studies Obstructive Sleep Apnea, Vascular Aneurysm, Ischemia Reperfusion Injury.

Is NCT04630535 still recruiting?

NCT04630535 is currently recruiting now. Last updated 15 May 2025.

Last reviewed 2025-05-15 · How we verify

NCT04630535

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

OSA as a Remote Ischemic Preconditioning in Vascular Surgery

Recruiting now Last updated 15 May 2025

What this trial tests

trial testing aorto-bifemoral bypass surgery in Obstructive Sleep Apnea in 100 participants. Currently enrolling.

Timeline

1 November 2020

Primary endpoint
31 December 2025

31 January 2026

Quick facts

Lead sponsor	St. Anne's University Hospital Brno, Czech Republic
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	100
Start date	1 November 2020
Primary completion	31 December 2025
Estimated completion	31 January 2026
Sites	1 location across Czechia

Drugs / interventions tested

aorto-bifemoral bypass surgery

Conditions studied

Obstructive Sleep Apnea — all drugs for Obstructive Sleep Apnea →
Vascular Aneurysm — all drugs for Vascular Aneurysm →
Ischemia Reperfusion Injury — all drugs for Ischemia Reperfusion Injury →

Sponsor

St. Anne's University Hospital Brno, Czech Republic

Who can join

18 and older, any sex, with Obstructive Sleep Apnea or Vascular Aneurysm. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ischemia and reperfusion (I/R) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure. Remote ischemic preconditioning (short periods of ischemia in anticipation of longer period of ischemia) may act protectively against ischemia. Studies of ischemic preconditioning in patients with AAA are conflicting. Obstructive sleep apnea (OSA) is a sleep disordered breathing syndrome which may have a protective effect against ischemia. The investigators hypothesize that I/R injury will be less pronounced in patients who have OSA and that the extent of I/R injury will inversely correlate with OSA severity. Accordingly, the aim of this study is to compare postoperative complications and markers of I/R in patients undergoing elective AAA repair who do and do not have OSA.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Obstructive Sleep Apnea

Currently open trials in the same condition.

NCT07195253 — Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome · recruiting
NCT07273019 — Tongue Muscular Assessment in Children With Sleep Disordered Breathing · NA · recruiting
NCT07447011 — Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea · NA · recruiting
NCT07397780 — RPMO2 Oximeter Accuracy During Sleep 1 Trial · active not recruiting
NCT06698809 — Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness · NA · recruiting

Other St. Anne's University Hospital Brno, Czech Republic trials

Trials by the same sponsor.

NCT07315542 — Diagnostic and Therapeutic Targets in Cartilaginous Tumours · recruiting
NCT06989229 — The Effect of Perioperative Nutritional Care on Recovery After Knee and Hip Replacement Surgery · recruiting
NCT06579274 — Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid Hemorrhage · Phase 2 · not yet recruiting
NCT06702059 — Cardiopulmonary Exercise Testing in Cardiosurgery Patients · recruiting
NCT05861089 — Rest PETCO2 As a Predictor of Post-operative Complications · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04630535 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by St. Anne's University Hospital Brno, Czech Republic
Last refreshed: 15 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04630535.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing