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NCT04612140
STereotactic Ablative Radiosurgery of Recurrent Ventricular Tachycardia in Structural Heart Disease
NA trial testing Radiosurgery in Ventricular Tachycardia in 22 participants. Completed in 30 June 2024.
30 June 2024
Quick facts
| Lead sponsor | University Hospital Ostrava |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 1 October 2020 |
| Primary completion | 30 June 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 2 locations across Czechia |
Drugs / interventions tested
- Radiosurgery
- Repeated catheter ablation
Conditions studied
- Ventricular Tachycardia — all drugs for Ventricular Tachycardia →
Sponsor
University Hospital Ostrava
Who can join
20 and older, any sex, with Ventricular Tachycardia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A multicentre trial on clinical effects of radiosurgical ablation of ventricular tachycardia (VT).
Publications & conference data
7 peer-reviewed publications reference this trial (live from Europe PMC):
-
STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe.
Grehn M, Mandija S, Miszczyk M, Krug D, et al · · 2023 · cited 60× · PMID 36879464 · DOI 10.1093/europace/euac238 -
Clinical Evidence behind Stereotactic Radiotherapy for the Treatment of Ventricular Tachycardia (STAR)-A Comprehensive Review.
Miszczyk M, Jadczyk T, Gołba K, Wojakowski W, et al · · 2021 · cited 23× · PMID 33802802 · DOI 10.3390/jcm10061238 -
Stereotactic arrhythmia radioablation and its implications for modern cardiac electrophysiology: results of an EHRA survey.
Kovacs B, Lehmann HI, Manninger M, Saguner AM, et al · · 2024 · cited 6× · PMID 38666444 · DOI 10.1093/europace/euae110 -
Non-Oncological Radiotherapy: A Review of Modern Approaches.
Nardone V, D'Ippolito E, Grassi R, Sangiovanni A, et al · · 2022 · cited 5× · PMID 36294816 · DOI 10.3390/jpm12101677 -
Radiation therapy for ventricular arrhythmias.
Liulu X, Balaji P, Barber J, De Silva K, et al · · 2024 · cited 1× · PMID 38698577 · DOI 10.1111/1754-9485.13662 -
Oral Abstracts for the 17th Asia Pacific Heart Rhythm Society (APHRS) Scientific Sessions
· 2025 -
Poster presentation
· 2023
Verify or expand the search:
- PubMed search for NCT04612140
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Ventricular Tachycardia
Currently open trials in the same condition.
- NCT07201506 — Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation · NA · recruiting
- NCT06360939 — Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease · NA · recruiting
- NCT07116525 — A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter · NA · recruiting
- NCT06891456 — Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia · NA · recruiting
- NCT06592001 — Assessment of a Chronically Implanted Parasternally Delivered EV-ICD Lead (ASCEND EV) Study · NA · active not recruiting
Other University Hospital Ostrava trials
Trials by the same sponsor.
- NCT07177183 — Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure · NA · recruiting
- NCT07374289 — On Scene ECPR in Ostrava · NA · recruiting
- NCT07041086 — Prehospital ECPR in Moravia Silesia Region · recruiting
- NCT07009652 — Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian · recruiting
- NCT06921746 — Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04612140 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Ostrava
- Last refreshed: 4 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04612140.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing