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NCT04603898
Oxalate Formation From Ascorbic Acid
NA trial testing Low Oxalate Diet in Kidney Stone in 136 participants. Currently enrolling.
1 August 2026
Quick facts
| Lead sponsor | University of Alabama at Birmingham |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 136 |
| Start date | 15 November 2021 |
| Primary completion | 1 August 2026 |
| Estimated completion | 1 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Low Oxalate Diet
- Carbon-13 Ascorbic Acid Oral Load
Conditions studied
- Kidney Stone — all drugs for Kidney Stone →
Sponsor
University of Alabama at Birmingham
Who can join
19 and older, any sex, with Kidney Stone. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this basic research study is to determine the contribution of endogenous ascorbic acid (AA) turnover to urinary oxalate excretion in both normal BMI and obese adult non-stone formers and calcium oxalate stone formers. The studies proposed will use diets of known nutrient composition, a stable isotope of ascorbic acid (13C6-AA) and mass spectrometric techniques to quantify ascorbic acid turnover to oxalate.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04603898
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other trials of Low Oxalate Diet
Trials testing the same drug.
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- NCT05417568 — Oxalate-Driven Host Responses in Kidney Stone Disease · NA · recruiting
- NCT04051346 — Dietary Oxalate and Innate Immunity in Kidney Stone Disease · NA · active not recruiting
Other recruiting trials for Kidney Stone
Currently open trials in the same condition.
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- NCT06576661 — Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Be · NA · recruiting
- NCT06210009 — Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease · NA · recruiting
- NCT07238803 — Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones. · NA · recruiting
Other University of Alabama at Birmingham trials
Trials by the same sponsor.
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- NCT06320951 — VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine · Phase 2 · not yet recruiting
- NCT07564934 — Leveraging Extended Reality Exergaming and Telehealth to Improve Physical Activity and Health in Children With Disabilit · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04603898 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alabama at Birmingham
- Last refreshed: 9 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04603898.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing