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NCT04590898
Peri-device Leakage Closure After LAAO
trial testing Peri-device leakage closure after left atrial appendage occlusion in Atrial Fibrillation in 85 participants. Completed in 1 September 2021.
1 September 2021
Quick facts
| Lead sponsor | Cardiovascular Center Frankfurt |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 85 |
| Start date | 27 September 2020 |
| Primary completion | 1 September 2021 |
| Estimated completion | 1 September 2021 |
| Sites | 16 locations across Denmark, United Kingdom, Germany, Poland, Switzerland, United States, Spain |
Drugs / interventions tested
- Peri-device leakage closure after left atrial appendage occlusion
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
- Stroke — all drugs for Stroke →
- Bleeding — all drugs for Bleeding →
- Leakage of Cardiac Device — all drugs for Leakage of Cardiac Device →
Sponsor
Cardiovascular Center Frankfurt
Who can join
Adults 18 to 100, any sex, with Atrial Fibrillation or Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators thought to evaluate the safety and feasibility of peri-device leakage closure after left atrial appendage occlusion (LAAO, either surgical or interventional) with different devices.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Safety and feasibility of peri-device leakage closure after LAAO: an international, multicentre collaborative study.
Piayda K, Sievert K, Della Rocca DG, Adeola OG, et al · · 2021 · cited 20× · PMID 34219662 · DOI 10.4244/eij-d-21-00286
Verify or expand the search:
- PubMed search for NCT04590898
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Cardiovascular Center Frankfurt trials
Trials by the same sponsor.
- NCT05014477 — Therapy Strategies After LAA Occluder Device Embolization · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04590898 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cardiovascular Center Frankfurt
- Last refreshed: 22 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04590898.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing