NCT04583371

The Use of Pulmonary Hyperinflation With the Mechanical Ventilator in Cardiac Patients

Status unknown NA Last updated 12 October 2020

What this trial tests

NA trial testing MECHANICAL PULMONARY HYPERINFLUATION in Heart Diseases in 50 participants. Status unknown.

Timeline

1 July 2020

Primary endpoint
30 January 2021

1 March 2021

Quick facts

Lead sponsor	Instituto de Cardiologia do Rio Grande do Sul
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	50
Start date	1 July 2020
Primary completion	30 January 2021
Estimated completion	1 March 2021
Sites	1 location across Brazil

Drugs / interventions tested

• MECHANICAL PULMONARY HYPERINFLUATION

Conditions studied

• Heart Diseases — all drugs for Heart Diseases →

Sponsor

Instituto de Cardiologia do Rio Grande do Sul — full company profile →

Who can join

18 and older, any sex, with Heart Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Mechanical ventilation (MV) is used to reduce work and reverse or prevent fatigue of the respiratory muscles, decrease oxygen consumption and maintain gas exchange. In addition to the benefits given to patients undergoing MV, there is a high risk of accumulating bronchial secretions, related to pathology and / or therapeutic intervention. Pulmonary hyperinflation is widespread in patients in intensive care centers (ICUs) as a bronchial hygiene therapy, being used in 40% of 64 Australian ICUs as demonstrated by Dennis et al., Through contact with physical therapists. Mechanical hyperinflation associated with tracheal aspiration is able to increase the amount of secretion aspirated when compared to isolated aspiration in patients undergoing mechanical ventilation. To assess whether the pulmonary hyperinflation maneuver with the mechanical ventilator, compared to isolated tracheal aspiration, increases the removal of secretions. To evaluate whether the use of the pulmonary hyperinflation maneuver in the mechanical ventilator is hemodynamically stable through the collection in two moments of the variables of heart rate (HR), mean arterial pressure (MAP), peripheral saturation (SpO2), respiratory rate (RF) that will be analyzed from the postoperative unit's multiparametric monitor.

Evaluate the change in respiratory mechanics through collection in two moments after the mechanical hyperinflation technique through dynamic compliance (Cdyn), tidal air volume (VAC), peak pressure (Ppico). The population will consist of patients from the Post-Operative Unit (UPO), from the Institute of Cardiology, of both sexes, over 18 years old, mechanically ventilated and the sample consisting of 50 individuals. These will be submitted to the use of the pulmonary hyperinflation maneuver in the mechanical ventilator. Randomized crossover clinical trial.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.