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NCT06917729: CardioBreath
Breathing Exercises of CardioBreath Application on Autonomic and Vascular Function in Hypertension
NA trial testing CardioBreath in Hypertension in 66 participants. Not yet recruiting.
20 July 2027
Quick facts
| Lead sponsor | Instituto de Cardiologia do Rio Grande do Sul |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 66 |
| Start date | 1 August 2025 |
| Primary completion | 20 July 2027 |
| Estimated completion | 20 September 2027 |
| Sites | 2 locations across Brazil |
Drugs / interventions tested
- CardioBreath
Conditions studied
- Hypertension — all drugs for Hypertension →
- Pre Hypertension — all drugs for Pre Hypertension →
Sponsor
Instituto de Cardiologia do Rio Grande do Sul — full company profile →
Who can join
Adults 18 to 60, any sex, with Hypertension or Pre Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hypertension is one of the greatest public health challenges, affecting more than one billion people worldwide and representing a significant financial and public health burden. It is responsible for a high number of cardiovascular events, such as heart attacks and strokes. Although pharmacological treatment is effective, non-pharmacological interventions are essential for the sustainable management of blood pressure, especially in its early stages. Respiratory exercises have shown potential in reducing blood pressure and improving cardiac vagal modulation, promoting cardiovascular health benefits. This study aims to evaluate the effectiveness of guided respiratory exercises using the CardioBreath app in improving vagal modulation and reducing arterial stiffness in adults with prehypertension or hypertension over six weeks. This is a randomized clinical trial involving adults with prehypertension or hypertension, divided into intervention and control groups. The intervention group will use CardioBreath to perform daily breathing exercises, with weekly remote monitoring. Assessments will include heart rate variability parameters, baroreflex sensitivity, pulse wave velocity, and quality of life. It is expected that the use of the app will significantly improve vagal modulation and arterial stiffness, demonstrating the potential of this intervention for the non-pharmacological management of hypertension. The use of CardioBreath may offer an accessible and effective alternative for blood pressure control, with the potential to be integrated into public health programs focused on low-cost, highly accessible interventions for the prevention and management of hypertension.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06917729
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Instituto de Cardiologia do Rio Grande do Sul trials
Trials by the same sponsor.
- NCT06497946 — Effects of SlimTrack® Platform on Diet Adherence, Anthropometry and Arterial Stiffness in Postmenopausal Women · NA · recruiting
- NCT06282302 — Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People · NA · unknown
- NCT06139653 — CardioBreathApp vs IMT in Heart Failure · NA · completed
- NCT03672760 — Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity · NA · recruiting
- NCT07147595 — Chronic Effect of Isometric Exercise on Blood Pressure in Patients With Hypertension · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06917729 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto de Cardiologia do Rio Grande do Sul
- Last refreshed: 8 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06917729.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing