18 and older, any sex, with Portal Hypertension or Chronic Advanced Liver Disease. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Liver Stiffness Measurements for Participants With Compensated Advanced Chronic Liver Disease With and Without Esophageal Varices Upon Esophagogastroduodenoscopy (EGD)Primary· one day
Comparing the performance of Velacur by Sonic Incytes to transient elastography via FibroScan® in the same patient population to determine if either test is more accurate in correlating with compensated advanced chronic liver disease (cACLD) for participants with and without esophageal varices.
liver stiffness with Velacur
Group
Value
95% CI
Participants Without Evidences of Esophageal Varices
9.6
± 3.9
Participants With Evidence of Esophageal Varices
10.1
± 3.2
liver stiffness with FibroScan
Group
Value
95% CI
Participants Without Evidences of Esophageal Varices
26.5
± 21.9
Participants With Evidence of Esophageal Varices
43.3
± 23.5
Platelet Count for Participants With Compensated Advanced Chronic Liver DiseasePrimary· one day
Comparing the platelet count in the same patient population to determine Velacur's accuracy in correlating with compensated advanced chronic liver disease (cACLD) for participants with and without esophageal varices
Group
Value
95% CI
Participants With Evidence of Esophageal Varices
91.2
± 37.7
Participants Without Evidence of Esophageal Varices
138
± 71
Sponsor's own description
This is a cross sectional study that evaluates the relationship between LSM (liver stiffness measurement) by Liver Incytes in patients with cACLD (compensated advanced chronic liver disease) and manifestations of portal hypertension.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
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Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indiana University
Last refreshed: 5 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04576897.