Last reviewed · How we verify
NCT04575753
Evaluating the Role of Pre-existing Resolvins in the Resolution of ICU Delirium
trial testing Study group in Delirium. Withdrawn.
30 May 2024
Quick facts
| Lead sponsor | Université Libre de Bruxelles |
|---|---|
| Status | Withdrawn |
| Study type | OBSERVATIONAL |
| Start date | 7 October 2023 |
| Primary completion | 30 May 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- Study group — full drug profile →
Conditions studied
- Delirium — all drugs for Delirium →
Sponsor
Université Libre de Bruxelles — full company profile →
Who can join
18 and older, any sex, with Delirium. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
As patient management is improving, more and more ICU survivors are being confronted with cognitive dysfunction and this well after their hospital stay. In the ICU, delirium rates have been reported to be as high at 81%. Delirium is associated with patient and family stress, increased hospital costs, increased duration of stay, escalation of care and increased mortality and morbidity. The physiopathology of ICU cognitive impairment is complex and involves an inflammatory cascade Recently, the role of 'resolvins' derived from omega-3 fatty acids has been studied in the resolution of inflammation. Therefore, this hypothesis of this study is that ICU patients with higher serum levels of resolvins at ICU admission, ICU day 2 and day 5 will have a lesser degree of cognitive impairment on day 5 of ICU stay.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology.
Dobrev D, Heijman J, Hiram R, Li N, et al · · 2023 · cited 207× · PMID 36109633 · DOI 10.1038/s41569-022-00759-w
Verify or expand the search:
- PubMed search for NCT04575753
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Study group
Trials testing the same drug.
- NCT06403085 — Proprioceptive Exercises in Stringed Instrument Performers · NA · recruiting
- NCT04598139 — Safer Use of Medication in Pediatric Patients at Home · unknown
- NCT05122299 — the Effect of coenzymeq10/Collagen Hydrogel on Bone Regeneration in Extraction Socket · NA · completed
- NCT05139511 — Analysis of the Results of Intense Pulsed Light Treatment Previously to Laser Refractive Surgery · NA · unknown
- NCT05784493 — Pain After Laparoscopic Hysterectomy · NA · completed
Other recruiting trials for Delirium
Currently open trials in the same condition.
- NCT07348471 — Fecal Microbiota Transplantation for the Treatment of ICU Delirium · NA · recruiting
- NCT06969287 — Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery · Phase 3 · recruiting
- NCT07369258 — Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit · NA · recruiting
- NCT07488468 — Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures · recruiting
- NCT07136207 — Development and Validation of Delirium Recognition Using Computer Vision in Neuro-critical Patients · recruiting
Other Université Libre de Bruxelles trials
Trials by the same sponsor.
- NCT07568405 — The Effect of Remifentanil on the Objectively Measured Pressure Pain Threshold · NA · enrolling by invitation
- NCT07513974 — Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumptio · NA · recruiting
- NCT07236021 — e-Motion : Promoting Emotion Regulation in Chronic Cancer · NA · recruiting
- NCT06959069 — Impact of Intermittent Fasting on Sleep and Quality of Life · NA · recruiting
- NCT06666101 — Effects of n3 LC PUFAs on Inflammatory, Immune and Senescence Features in Polyvascular Older Subjects (OMSAGE) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04575753 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Université Libre de Bruxelles
- Last refreshed: 30 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04575753.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing