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NCT05122299
the Effect of coenzymeq10/Collagen Hydrogel on Bone Regeneration in Extraction Socket
NA trial testing Negative control group in Dental Implants in 18 participants. Completed in 1 September 2021.
1 September 2021
Quick facts
| Lead sponsor | Hams Hamed Abdelrahman |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 18 |
| Start date | 28 March 2021 |
| Primary completion | 1 September 2021 |
| Estimated completion | 1 September 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Negative control group
- Postive control
- Study group — full drug profile →
Conditions studied
- Dental Implants — all drugs for Dental Implants →
Sponsor
Hams Hamed Abdelrahman — full company profile →
Who can join
Adults 30 to 60, any sex, with Dental Implants. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To investigate the effect of CoQ10 in soft tissue healing and bone regeneration after extraction in diabetic patients seeking dental implants. Methods: This study will be a randomized controlled clinical trial, 18 patients will be divided equally into three groups. In-vitro studies will be performed to investigate the release of CoQ10 from collagen, swelling ratio, and evaluation of gelation behavior. The patients will undergo tooth extraction and filling of the socket with either collagen or CoQ10/collagen. Empty sockets will serve as a negative control. The bone regeneration of the socket will be determined by radiography, histology, histomorphometry, and polymerase chain reaction (PCR) for bone markers.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Smart Hydrogels for Bone Reconstruction via Modulating the Microenvironment.
Chen W, Zhang H, Zhou Q, Zhou F, et al · · 2023 · cited 68× · PMID 36996343 · DOI 10.34133/research.0089 -
The Effect of Coenzyme Q10/Collagen Hydrogel on Bone Regeneration in Extraction Socket Prior to Implant Placement in Type II Diabetic Patients: A Randomized Controlled Clinical Trial.
Ghanem M, Heikal L, Abdel Fattah H, El Ashwah A, et al · · 2022 · cited 9× · PMID 35683447 · DOI 10.3390/jcm11113059
Verify or expand the search:
- PubMed search for NCT05122299
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dental Implants
Currently open trials in the same condition.
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- NCT06808854 — Variable-thread Versus Standard Dental Implants for Replacing Missing Teeth · NA · recruiting
- NCT07088679 — Natural Bioactive Gel for Peri-Implantitis · NA · recruiting
- NCT06960460 — Study Evaluating the Performance and Safety in the Medium and Long Term of Global D ZygoFixU System · NA · recruiting
Other Hams Hamed Abdelrahman trials
Trials by the same sponsor.
- NCT07044882 — Hydrodynamic Piezoelectric Technique in Internal Sinus Lift · NA · not yet recruiting
- NCT07082634 — Immediate Implant Placement Using the Socket Shield Technique in Maxillary Esthetic Zone · NA · not yet recruiting
- NCT07044895 — Diode Laser Photocoagulation With Immediate Implant Placement · NA · not yet recruiting
- NCT06759311 — Two Different Minimal Invasive Techniques in Caries Removal of Primary Teeth · NA · active not recruiting
- NCT07103564 — The Effect of Local Melatonin Application Around Immediately Placed Implants in the Maxillary Premolar · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05122299 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hams Hamed Abdelrahman
- Last refreshed: 16 November 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05122299.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing