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NCT04573894

Diagnostic Performance of Plasma Procalcitonin for the Detection of Blood Cultures Contaminations

Completed Last updated 5 October 2020
What this trial tests

trial testing Procalcitonin dosage in Blood Culture Contamination in 147 participants. Completed in 5 September 2020.

Timeline
1 June 2020
Primary endpoint
31 July 2020
5 September 2020

Quick facts

Lead sponsorCentral Hospital, Nancy, France
StatusCompleted
Study typeOBSERVATIONAL
Enrollment147
Start date1 June 2020
Primary completion31 July 2020
Estimated completion5 September 2020
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Central Hospital, Nancy, France

Who can join

18 and older, any sex, with Blood Culture Contamination or Bacteremia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In blood cultures, species considered as potentially contaminating (coagulase negative staphylococci (CNS), Bacillus spp., Corynebacterium spp., Cutibacterium acnes, Micrococcus spp., viridans group streptococci, and Clostridium perfringens) can, however, be responsable for true bacteremia. Blood levels of the prohormone procalcitonin (PCT) markedly increase in the early stages of bacterial infections. The aim of our study is to determine the role of plasma PCT as a biomarker differentiating blood culture contaminations from true bacteremia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Accuracy of procalcitonin for diagnosing peripheral blood culture contamination among patients with positive blood culture for potential contaminants.
    Berthezène C, Aissa N, Manteaux AE, Guéant JL, et al · · 2021 · cited 5× · PMID 34524647 · DOI 10.1007/s15010-021-01697-4

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Other recruiting trials for Blood Culture Contamination

Currently open trials in the same condition.

Other Central Hospital, Nancy, France trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04573894.

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