NCT04572412 is a NA clinical trial of Low dose Radiotherapy in Covid19, sponsored by Lancashire Teaching Hospitals NHS Foundation Trust.

Who is sponsoring NCT04572412?

NCT04572412 is sponsored by Lancashire Teaching Hospitals NHS Foundation Trust.

What drugs are being tested in NCT04572412?

Interventions in NCT04572412: Low dose Radiotherapy.

Is NCT04572412 still recruiting?

NCT04572412 is currently completed. Last updated 10 November 2022.

Last reviewed 2022-11-10 · How we verify

NCT04572412

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia

Completed NA Last updated 10 November 2022

What this trial tests

NA trial testing Low dose Radiotherapy in Covid19 in 2 participants. Completed in 30 June 2022.

Timeline

25 November 2020

Primary endpoint
30 June 2022

30 June 2022

Quick facts

Lead sponsor	Lancashire Teaching Hospitals NHS Foundation Trust
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	health services research
Enrollment	2
Start date	25 November 2020
Primary completion	30 June 2022
Estimated completion	30 June 2022
Sites	1 location across United Kingdom

Drugs / interventions tested

Low dose Radiotherapy

Conditions studied

Covid19 — all drugs for Covid19 →

Sponsor

Lancashire Teaching Hospitals NHS Foundation Trust

Who can join

50 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to document the feasibility and tolerability of low dose thoracic radiotherapy in patients with WHO level 5 COVID 19 infections.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

Low-dose radiation therapy for COVID-19 pneumonia: a pilot study.
Sharma DN, Guleria R, Wig N, Mohan A, et al · · 2021 · cited 36× · PMID 34545760 · DOI 10.1259/bjr.20210187
The Role of Ionizing Radiation for Diagnosis and Treatment against COVID-19: Evidence and Considerations.
Chalkia M, Arkoudis NA, Maragkoudakis E, Rallis S, et al · · 2022 · cited 7× · PMID 35159277 · DOI 10.3390/cells11030467
COVID-19: The Disease, the Immunological Challenges, the Treatment with Pharmaceuticals and Low-Dose Ionizing Radiation.
Yu J, Azzam EI, Jadhav AB, Wang Y. · · 2021 · cited 5× · PMID 34571861 · DOI 10.3390/cells10092212
COVID-19-Associated Pneumonia: Radiobiological Insights.
François S, Helissey C, Cavallero S, Drouet M, et al · · 2021 · cited 3× · PMID 34113249 · DOI 10.3389/fphar.2021.640040
Low Dose Radiation Therapy for COVID-19 Pneumonia: A Pilot Study
Sharma DN, Guleria R, Wig N, Mohan A, et al · · 2020 · cited 1× · DOI 10.1101/2020.11.16.20231514
[Low dose radiotherapy for COVID-19 pneumopathy: Biological rationale and literature review].
Miran C, Bonnet É, Allignet B, Clippe S, et al · · 2021 · PMID 33903009 · DOI 10.1016/j.canrad.2021.03.005

Verify or expand the search:

Other trials of Low dose Radiotherapy

Trials testing the same drug.

NCT03040804 — Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa · NA · terminated

Other recruiting trials for Covid19

Currently open trials in the same condition.

NCT03305341 — Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologic Mix · EARLY_PHASE1 · active not recruiting
NCT06482138 — Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation · NA · recruiting
NCT04924803 — Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs · NA · active not recruiting
NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting

Other Lancashire Teaching Hospitals NHS Foundation Trust trials

Trials by the same sponsor.

NCT06445205 — Utilising Volumetric Absorptive Microsampling (VAMS) Technology to Monitor Tacrolimus and Creatinine · suspended
NCT06288464 — Enteral Feeding of Fibre to Improve Microbiota · NA · recruiting
NCT06445985 — Hydrotherapy in Duchenne Muscular Dystrophy (DMD) · NA · active not recruiting
NCT05686941 — Is Laryngeal Ultrasound Useful in the Assessment for ILO? A Protocol for a Two-stage Exploratory Pilot Study · unknown
NCT06263920 — Neurofrailty: A Study of Late-onset Epilepsy and Its Associations · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04572412 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Lancashire Teaching Hospitals NHS Foundation Trust
Last refreshed: 10 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04572412.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing