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NCT03040804: RTHS

Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa

Terminated NA Results posted Last updated 1 November 2021
What this trial tests

NA trial testing Low dose Radiotherapy in Hidradenitis Suppurativa in 2 participants. Terminated before completion.

Timeline
1 March 2017
Primary endpoint
21 December 2020
21 December 2020

Quick facts

Lead sponsorMontefiore Medical Center
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment2
Start date1 March 2017
Primary completion21 December 2020
Estimated completion21 December 2020
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Montefiore Medical Center

Who can join

20 and older, any sex, with Hidradenitis Suppurativa or Hidradenitis. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Participants With HS Who Experience Treatment-related Grade ≥3 Adverse Events During Radiotherapy or Within 3 Months of Radiotherapy Completion, Assessed Using CTCAE Version 4.0 Primary · follow up for 3-6 months post treatment

Number of participants with HS who experience treatment-related CTCAE version 4.0 Grade ≥3 adverse events during radiotherapy or within 3 months of radiotherapy completion. Common Terminology Criteria for Adverse Events (CTCAE) is an internationally accepted standard for defining and categorizing adverse events based on severity of reported adverse events. The grading scheme is from 1 (least severe) to 5 (most severe). For radiotherapy associated adverse events, CTCAE version 4.0 will be applied to "Rash: dermatitis associated with radiation". Grade 1. Mild: Faint erythema or dry desquamation

GroupValue95% CI
Low Dose Radiotherapy2

Sponsor's own description

To establish the safety of radiotherapy in the treatment of advanced hidradenitis suppurativa. Patients will receive radiotherapy treatment over one week and then they will be followed for the next three months.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa-Part II: Procedural and Wound Care Therapies.
    Fragoso NM, Masson R, Gillenwater TJ, Shi VY, et al · · 2023 · cited 3× · PMID 37402030 · DOI 10.1007/s13555-023-00957-5

Verify or expand the search:

Other trials of Low dose Radiotherapy

Trials testing the same drug.

Other recruiting trials for Hidradenitis Suppurativa

Currently open trials in the same condition.

Other Montefiore Medical Center trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03040804.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing